PMM1 Protein (AA 1-262) (His tag)
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- Antigène Voir toutes PMM1 Protéines
- PMM1 (Phosphomannomutase 1 (PMM1))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-262
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette PMM1 protéine est marqué à la His tag.
- Fonction
- Recombinant Human Phosphomannomutase 1/PMM1 (C-6His)
- Séquence
- MAVTAQAARR KERVLCLFDV DGTLTPARQK IDPEVAAFLQ KLRSRVQIGV VGGSDYCKIA EQLGDGDEVI EKFDYVFAEN GTVQYKHGRL LSKQTIQNHL GEELLQDLIN FCLSYMALLR LPKKRGTFIE FRNGMLNISP IGRSCTLEER IEFSELDKKE KIREKFVEAL KTEFAGKGLR FSRGGMISFD VFPEGWDKRY CLDSLDQDSF DTIHFFGNET SPGGNDFEIF ADPRTVGHSV VSPQDTVQRC REIFFPETAH EAVEHHHHHH
- Attributs du produit
- Recombinant Human Phosphomannomutase 1/PMM1 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Ala262) of Human PMM1 fused with a His tag at the C-terminus.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- Stérilité
- 0.2 μm filtered
- niveau d'endotoxine
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product PMM1 Protéine
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 1 mM DTT, pH 8.0.
- Agent conservateur
- Dithiothreitol (DTT)
- Précaution d'utilisation
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Stock
- -80 °C
- Stockage commentaire
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Date de péremption
- 6 months
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- Antigène
- PMM1 (Phosphomannomutase 1 (PMM1))
- Autre désignation
- Phosphomannomutase 1/PMM1 (PMM1 Produits)
- Synonymes
- Sec53 Protein, C77612 Protein, phosphomannomutase 1 Protein, phosphomannomutase 1 L homeolog Protein, PMM1 Protein, pmm1 Protein, Pmm1 Protein, pmm1.L Protein
- Sub Type
- Fusionprotein
- Sujet
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Phosphomannomutase 1 (PMM1) blongs to the eukaryotic PMM family. Phosphomannomutase 1 can catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose which required for a number of critical mannosyl transfer reactions. PMM1 is highly expressed in liver, heart, brain, and pancreas, but lower expression in skeletal muscle. In addition, PMM1 may be responsible for the degradation of glucose-1,6 bisphosphate in ischemic brain.
Alternative Names: Phosphomannomutase 1, PMM 1, PMMH-22, PMM1, PMMH22 - Poids moléculaire
- 30.8 kDa
- UniProt
- Q92871
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