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PMM1 Protein (AA 1-262) (His tag)

PMM1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN1097358
  • Antigène Voir toutes PMM1 Protéines
    PMM1 (Phosphomannomutase 1 (PMM1))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-262
    Origine
    • 6
    • 1
    Humain
    Source
    • 3
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette PMM1 protéine est marqué à la His tag.
    Fonction
    Recombinant Human Phosphomannomutase 1/PMM1 (C-6His)
    Séquence
    MAVTAQAARR KERVLCLFDV DGTLTPARQK IDPEVAAFLQ KLRSRVQIGV VGGSDYCKIA EQLGDGDEVI EKFDYVFAEN GTVQYKHGRL LSKQTIQNHL GEELLQDLIN FCLSYMALLR LPKKRGTFIE FRNGMLNISP IGRSCTLEER IEFSELDKKE KIREKFVEAL KTEFAGKGLR FSRGGMISFD VFPEGWDKRY CLDSLDQDSF DTIHFFGNET SPGGNDFEIF ADPRTVGHSV VSPQDTVQRC REIFFPETAH EAVEHHHHHH
    Attributs du produit
    Recombinant Human Phosphomannomutase 1/PMM1 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Ala262) of Human PMM1 fused with a His tag at the C-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    Stérilité
    0.2 μm filtered
    niveau d'endotoxine
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product PMM1 Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 1 mM DTT, pH 8.0.
    Agent conservateur
    Dithiothreitol (DTT)
    Précaution d'utilisation
    This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Stock
    -80 °C
    Stockage commentaire
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    PMM1 (Phosphomannomutase 1 (PMM1))
    Autre désignation
    Phosphomannomutase 1/PMM1 (PMM1 Produits)
    Synonymes
    Sec53 Protein, C77612 Protein, phosphomannomutase 1 Protein, phosphomannomutase 1 L homeolog Protein, PMM1 Protein, pmm1 Protein, Pmm1 Protein, pmm1.L Protein
    Sub Type
    Fusionprotein
    Sujet
    Phosphomannomutase 1 (PMM1) blongs to the eukaryotic PMM family. Phosphomannomutase 1 can catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose which required for a number of critical mannosyl transfer reactions. PMM1 is highly expressed in liver, heart, brain, and pancreas, but lower expression in skeletal muscle. In addition, PMM1 may be responsible for the degradation of glucose-1,6 bisphosphate in ischemic brain.
    Alternative Names: Phosphomannomutase 1, PMM 1, PMMH-22, PMM1, PMMH22
    Poids moléculaire
    30.8 kDa
    UniProt
    Q92871
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