PMM2 Protein (AA 1-246) (His tag)

N° du produit ABIN1097361

Détail du produit

Antigène: PMM2 (Phosphomannomutase 2 (PMM2))

Type de proteíne: Recombinant

Attributs du protein: AA 1-246

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PMM2 protéine est marqué à la His tag.

Fonction: Recombinant Human Phosphomannomutase 2/PMM2 (C-6His)

Séquence: MAAPGPALCL FDVDGTLTAP RQKITKEMDD FLQKLRQKIK IGVVGGSDFE KVQEQLGNDV VEKYDYVFPE NGLVAYKDGK LLCRQNIQSH LGEALIQDLI NYCLSYIAKI KLPKKRGTFI EFRNGMLNVS PIGRSCSQEE RIEFYELDKK ENIRQKFVAD LRKEFAGKGL TFSIGGQISF DVFPDGWDKR YCLRHVENDG YKTIYFFGDK TMPGGNDHEI FTDPRTMGYS VTAPEDTRRI CELLFSLEHH HHHH

Attributs du produit: Recombinant Human Phosphomannomutase 2/PMM2 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Ser246) of Human PMM2 fused with a His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: -80 °C

Stockage commentaire: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: PMM2 (Phosphomannomutase 2 (PMM2))

Autre désignation: PMM2 (PMM2 Produits)

Synonymes: cb626 Protein, zgc:56149 Protein, MGC82869 Protein, pmm2 Protein, CDG1 Protein, CDG1a Protein, CDGS Protein, PMI Protein, PMI1 Protein, PMM 2 Protein, AI585868 Protein, C86848 Protein, phosphomannomutase 2 Protein, phosphomannomutase 2 S homeolog Protein, pmm2 Protein, PMM2 Protein, pmm2.S Protein, PTRG_02815 Protein, Tsp_00480 Protein, Pmm2 Protein

Sub Type: Fusionprotein

Sujet: Phosphomannomutase 2 (PMM2) is an enzyme that is a member of the highly variable methyltransferase superfamily. PMM2 is a cytoplasmic protein and catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate.In addition, PMM2 involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose that required for a number of critical mannosyl transfer reactions. Defects in PMM2 can results in congenital disorder of glycosylation type 1A (CDG1A). Congenital disorders of glycosylation are metabolic deficiencies in glycoprotein biosynthesis that usually cause severe mental and psychomotor retardation.
Alternative Names: Phosphomannomutase 2, PMM 2, PMM2

Poids moléculaire: 29.1 kDa

UniProt: O15305