PPCDC Protein (AA 1-204) (His tag)

N° du produit ABIN1097376

Détail du produit

Antigène: PPCDC (phosphopantothenoylcysteine Decarboxylase (PPCDC))

Type de proteíne: Recombinant

Attributs du protein: AA 1-204

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PPCDC protéine est marqué à la His tag.

Fonction: Recombinant Human Phosphopantothenoylcysteine Decarboxylase/PPC-DC (N-6His)

Séquence: MGSSHHHHHH SSGLVPRGSH MEPKASCPAA APLMERKFHV LVGVTGSVAA LKLPLLVSKL LDIPGLEVAV VTTERAKHFY SPQDIPVTLY SDADEWEMWK SRSDPVLHID LRRWADLLLV APLDANTLGK VASGICDNLL TCVMRAWDRS KPLLFCPAMN TAMWEHPITA QQVDQLKAFG YVEIPCVAKK LVCGDEGLGA MAEVGTIVDK VKEVLFQHSG FQQS

Attributs du produit: Recombinant Human Phosphopantothenoylcysteine Decarboxylase/PPC-DC is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Ser204) of Human PPCDC fused with a His tag at the N-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 50 mM NaCl, 1 mM DTT, 10 % Glycerol, pH 8.0.

Agent conservateur: Dithiothreitol (DTT)

Précaution d'utilisation: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: -80 °C

Stockage commentaire: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: PPCDC (phosphopantothenoylcysteine Decarboxylase (PPCDC))

Autre désignation: PPC-DC (PPCDC Produits)

Synonymes: MDS018 Protein, 1810057I13Rik Protein, 8430432M10Rik Protein, RGD1306267 Protein, phosphopantothenoylcysteine decarboxylase Protein, PPCDC Protein, Ppcdc Protein

Sub Type: Fusionprotein

Sujet: Phosphopantothenoylcysteine Decarboxylase (PPC-DC) is an essential enzyme in the biosynthesis of Coenzyme A and catalyzes the decarboxylation of PPC to Phosphopantetheine. PPC-DC catalyzes the decarboxylation of the Cysteine moiety of 4-Phosphopantothenoylcysteine (PPC) to form 4-Phosphopantetheine (PPantSH), this reaction forms part of the biosynthesis of Coenzyme A. The enzyme is a member of the larger family of Cysteine Decarboxylases including the Lantibiotic-Biosynthesizing enzymes EpiD and MrsD, all of which use a tightly bound Flavin cofactor to oxidize the Thiol moiety of the substrate to a Thioaldehyde.
Alternative Names: Phosphopantothenoylcysteine Decarboxylase, PPC-DC, PPCDC, COAC

Poids moléculaire: 24.6 kDa

UniProt: Q96CD2

Pathways: Ribonucleoside Biosynthetic Process