ST6GAL1 Protein (AA 27-406) (His tag)

N° du produit ABIN1097583

Détail du produit

Antigène: ST6GAL1 (ST6 beta-Galactosamide alpha-2,6-Sialyltranferase 1 (ST6GAL1))

Type de proteíne: Recombinant

Attributs du protein: AA 27-406

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette ST6GAL1 protéine est marqué à la His tag.

Fonction: Recombinant Human β-Galactoside α-2,6-Sialyltransferase 1/ST6GAL1 (C-6His)

Séquence: KEKKKGSYYD SFKLQTKEFQ VLKSLGKLAM GSDSQSVSSS STQDPHRGRQ TLGSLRGLAK AKPEASFQVW NKDSSSKNLI PRLQKIWKNY LSMNKYKVSY KGPGPGIKFS AEALRCHLRD HVNVSMVEVT DFPFNTSEWE GYLPKESIRT KAGPWGRCAV VSSAGSLKSS QLGREIDDHD AVLRFNGAPT ANFQQDVGTK TTIRLMNSQL VTTEKRFLKD SLYNEGILIV WDPSVYHSDI PKWYQNPDYN FFNNYKTYRK LHPNQPFYIL KPQMPWELWD ILQEISPEEI QPNPPSSGML GIIIMMTLCD QVDIYEFLPS KRKTDVCYYY QKFFDSACTM GAYHPLLYEK NLVKHLNQGT DEDIYLLGKA TLPGFRTIHC VDHHHHHH

Attributs du produit: Recombinant Human beta-Galactoside alpha-2,6-Sialyltransferase 1/ST6GAL1 produced by transfected human cells is a secreted protein with sequence (Lys27-Cys406) of Human ST6GAL1 fused with a polyhistidine tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: -80 °C

Stockage commentaire: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: ST6GAL1 (ST6 beta-Galactosamide alpha-2,6-Sialyltranferase 1 (ST6GAL1))

Autre désignation: st6gal1 (ST6GAL1 Produits)

Synonymes: SIAT1 Protein, ST6GalI Protein, ST6N Protein, Siat1 Protein, siat1 Protein, zgc:136454 Protein, ST6GAL1 Protein, AW742324 Protein, St6Gal-I Protein, St6gal Protein, St6galI Protein, ST6 beta-galactoside alpha-2,6-sialyltransferase 1 Protein, ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 Protein, beta galactoside alpha 2,6 sialyltransferase 1 Protein, ST6GAL1 Protein, St6gal1 Protein, st6gal1 Protein

Sub Type: Fusionprotein

Sujet: The ST6GAL1 gene encodes beta-Galactosamide alpha-2,6-Sialyltransferase 1. It is a type II membrane protein and is localized to the trans-Golgi network. It catalyzes 2,6-sialylation of Galbeta1,4-GlcNAc structures on N-glycans. ST6GAL1 is highly expressed in the liver and other tissues. ST6GAL1 deficiency causes abnormalities in B-cell immunoreactivity. The expression and activity of ST6GAL1 are associated with tumor metastasis in breast and colon cancers. The majority of ST6GAL1 in the liver is cleaved and secreted into the serum and may be used as a biomarker for hepatitis diseases.
Alternative Names: Beta-Galactoside Alpha-2,6-Sialyltransferase 1, Alpha 2,6-ST 1, B-Cell Antigen CD75, CMP-N-Acetylneuraminate-Beta-Galactosamide-Alpha-2,6-Sialyltransferase 1, ST6Gal I, ST6GalI, Sialyltransferase 1, ST6GAL1, SIAT1

Poids moléculaire: 44.6 kDa

UniProt: P15907