CARD18 Protein (His tag)
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- Antigène Voir toutes CARD18 Protéines
- CARD18 (Caspase Recruitment Domain-Containing Protein 18 (ICEBERG) (CARD18))
- Type de proteíne
- Recombinant
- Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette CARD18 protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Pureté
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product CARD18 Protéine
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- Commentaires
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Synonyms: Caspase recruitment domain-containing protein 18, ICEBERG, pseudo-ICE, UNQ5804
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 1 MM DTT,10% glycerol, 0.1 M NaCl
- Stock
- 4 °C
- Stockage commentaire
- Avoid repeated freezing and thawing cycles.
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- Antigène
- CARD18 (Caspase Recruitment Domain-Containing Protein 18 (ICEBERG) (CARD18))
- Autre désignation
- CARD18 (CARD18 Produits)
- Synonymes
- ICEBERG Protein, UNQ5804 Protein, pseudo-ICE Protein, caspase recruitment domain family member 18 Protein, CARD18 Protein
- Sujet
- Caspase recruitment domain-containing protein 18, also known as CARD18, is a member of the death-domain-fold superfamily that is induced by proinflammatory stimuli. It consists essentially only of a CARD, inhibits generation of IL-1b by interacting with caspase-1 and preventing association with RIP 2. The association of CARD18 with caspase-1 is facilitated by the charge-charge interactions between the prodomain of caspase-1 and the surface charge of CARD18. Recombinant human CARD18 proetin, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Poids moléculaire
- 12.3 kDa (110aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_067546
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