Pallidin Protein (full length) (His tag)

N° du produit ABIN1098241

Détail du produit

Antigène: Pallidin (PLDN) (Pallidin Homolog (PLDN))

Type de proteíne: Recombinant

Attributs du protein: full length

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Pallidin protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Purification: purified by chromatography

Pureté: > 90 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: pallidin, HPS9, PA, PALLID

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 2 mM DTT, 10% glycerol, 100 mM NaCl

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: Pallidin (PLDN) (Pallidin Homolog (PLDN))

Autre désignation: PLDN (PLDN Produits)

Synonymes: CG14133 Protein, Dmel\\CG14133 Protein, LOC100226487 Protein, pldn Protein, BLOS6 Protein, HPS9 Protein, PA Protein, PALLID Protein, PLDN Protein, Pldn Protein, BLOC-1 Protein, Stx13bp1 Protein, pa Protein, pallidin Protein, CG14133 gene product from transcript CG14133-RB Protein, biogenesis of lysosomal organelles complex 1 subunit 6 Protein, pallidin homolog (mouse) Protein, biogenesis of lysosomal organelles complex-1, subunit 6, pallidin Protein, Pallidin Protein, BLOC1S6 Protein, pldn Protein, Bloc1s6 Protein

Sujet: PLDN (Pallidin) may play a role in intracellular vesicle trafficking. It interacts with Syntaxin 13 which mediates intracellular membrane fusion. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This protein involved in the development of lysosome-related organelles, such as melanosomes and platelet-dense granules. PLDN has been shown to interact with BLOC1S1, STX12, Dysbindin, CNO, BLOC1S2, MUTED and SNAPAP. Recombinant human PLDN protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 21.9kDa (192aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

NCBI Accession: NP_036520

Pathways: Synaptic Vesicle Exocytosis