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CKMT1A Protein (His tag)

CKMT1A Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
N° du produit ABIN1098309
  • Antigène Voir toutes CKMT1A Protéines
    CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))
    Type de proteíne
    Recombinant
    Origine
    • 3
    • 2
    • 2
    • 2
    • 2
    Humain
    Source
    • 10
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette CKMT1A protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Purification
    purified by chromatography
    Pureté
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product CKMT1A Protéine
  • Commentaires

    Synonyms: Creatine kinase U-type, mitochondrial, CKMT1, CKMT1B, UMTCK

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol
    Stock
    4 °C
    Stockage commentaire
    Avoid repeated freezing and thawing cycles.
  • Antigène
    CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))
    Autre désignation
    CKMT1A (CKMT1A Produits)
    Synonymes
    CKMT1 Protein, Mt-CK Protein, ScCKmit Protein, UbCKmit Protein, mi-CK Protein, Ckmt1 Protein, CKMT1B Protein, Mia-CK Protein, U-MtCK Protein, creatine kinase, mitochondrial 1A Protein, creatine kinase U-type, mitochondrial-like Protein, creatine kinase, mitochondrial 1, ubiquitous Protein, creatine kinase U-type, mitochondrial Protein, CKMT1A Protein, LOC100228000 Protein, Ckmt1 Protein, LOC100725326 Protein
    Sujet
    Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Recombinant human CKMT1A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Poids moléculaire
    45 kDa (403aa) confirmed by MALDI-TOF
    NCBI Accession
    NP_001015001
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