ACADSB Protein (His tag)

N° du produit ABIN1098335

Détail du produit

Antigène: ACADSB (Acyl-CoA Dehydrogenase, Short/branched Chain (ACADSB))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette ACADSB protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Purification: purified by chromatography

Pureté: > 90 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial, 2-MEBCAD, ACAD7, SBCAD

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 10% glycerol,1 MM DTT

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: ACADSB (Acyl-CoA Dehydrogenase, Short/branched Chain (ACADSB))

Autre désignation: ACADSB (ACADSB Produits)

Synonymes: 2-mebcad Protein, acad7 Protein, sbcad Protein, DDBDRAFT_0185291 Protein, DDBDRAFT_0237707 Protein, DDB_0185291 Protein, DDB_0237707 Protein, 2-MEBCAD Protein, ACAD7 Protein, SBCAD Protein, 1300003O09Rik Protein, BB066609 Protein, acyl-CoA dehydrogenase, short/branched chain Protein, acyl-CoA dehydrogenase short/branched chain Protein, acyl-coenzyme A dehydrogenase, short/branched chain Protein, acyl-CoA dehydrogenase Protein, acyl-CoA dehydrogenase, short/branched chain L homeolog Protein, acyl-Coenzyme A dehydrogenase, short/branched chain Protein, ACADSB Protein, acadsb Protein, sce1166 Protein, acadsb.L Protein, Acadsb Protein

Sujet: Short/branched chain specific acyl-CoA dehydrogenase(ACADSB), is a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. ACADSB catalyzes the degradation of L-isoleucine and has the highest affinity for (s)-2-methylbutyryl-CoA, isobutyryl-CoA and 2-methylhexanoyl-CoA as substrates. Defects in ACADSB are the cause of short/branched-chain acyl-CoA dehydrogenase deficiency (SBCADD), an autosomal recessive disorder characterized by an increase of 2-methylbutyrylglycine and 2-methylbutyrylcarnitine in blood and urine. Recombinant human ACADSB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 46.4 kDa (424aa)

NCBI Accession: NP_001600

Pathways: Monocarboxylic Acid Catabolic Process