CLNS1A Protein (His tag)

N° du produit ABIN1098452

Détail du produit

Antigène: CLNS1A (Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CLNS1A protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Purification: purified by chromatography

Pureté: > 90 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: Methylosome subunit pICln, CLCI, CLNS1B, Icln

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 10% glycerol, 2 mM DTT

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: CLNS1A (Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A))

Autre désignation: CLNS1A (CLNS1A Produits)

Synonymes: CLCI Protein, CLNS1B Protein, ICln Protein, 2610036D06Rik Protein, 2610100O04Rik Protein, Clci Protein, Clcni Protein, ICLN Protein, Icln Protein, pICln Protein, clci Protein, clns1b Protein, icln Protein, pIcIn Protein, chloride nucleotide-sensitive channel 1A Protein, chloride channel, nucleotide-sensitive, 1A Protein, chloride channel, nucleotide-sensitive, 1A L homeolog Protein, CLNS1A Protein, Clns1a Protein, clns1a.L Protein, clns1a Protein

Sujet: CLNS1A, also as known as, Methylosome subunit pICln, belongs to the pICln (TC 1.A.47) family. CLNS1A protein has functions in multiple regulatory pathways. This protein interaction with Sm proteins inhibits their assembly on U RNA and interferes with snRNP biogenesis. It is Inhibits the binding of survival motor neuron protein (SMN) to Sm proteins. And this protein is also found associated with the plasma membrane where it functions as a chloride current regulator. Recombinant human CLNS1A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 28.8kDa (261aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)

NCBI Accession: NP_001284

Pathways: Ribonucleoprotein Complex Subunit Organization