RAP2B Protein (His tag)

N° du produit ABIN1098540

Détail du produit

Antigène: RAP2B (RAP2B, Member of RAS Oncogene Family (RAP2B))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette RAP2B protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Purification: purified by chromatography

Pureté: > 95 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: Ras-related protein Rap-2b, RAP2B, member of RAS oncogene family

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 20% glycerol, 1 MM DTT

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: RAP2B (RAP2B, Member of RAS Oncogene Family (RAP2B))

Autre désignation: RAP2B (RAP2B Produits)

Synonymes: Rap2b Protein, wu:fi34c06 Protein, zgc:55550 Protein, RAP2B Protein, LOC100223676 Protein, 4021402C18Rik Protein, AA408554 Protein, RAP2B, member of RAS oncogene family S homeolog Protein, RAP2B, member of RAS oncogene family Protein, RAS-like, family 10, member A Protein, GTP-binding protein Rhes pseudogene Protein, rap2b.S Protein, rap2b Protein, RASL10A Protein, RAP2B Protein, LOC100223676 Protein, Rap2b Protein

Sujet: Ras-related protein Rap-2b, also known as RAP2B, belongs to a family of RAS-related genes. Unlike normal ras proteins that have a nontransforming glutamine residue at aa 61, Rap2B has a threonine residue in that position. This change makes the intrinsic GTPase activity for Rap2B lower, thereby allowing it to exist in the activated state for a longer period of time than normal ras proteins. RAP2B is a platelet protein that is activated by thrombin and involved in platelet activation. RAP2B may be a novel candidate oncogene that plays important roles in carcinogenesis through activation of NF-kappaB pathway. Recombinant human RAP2B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 22.9kDa (206aa) confirmed by MALDI-TOF

NCBI Accession: NP_002877