UBE2M Protein (His tag)

N° du produit ABIN1098637

Détail du produit

Antigène: UBE2M (ube2m) (Ubiquitin-Conjugating Enzyme E2M (ube2m))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette UBE2M protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Purification: purified by using conventional chromatography.

Pureté: > 95 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: NEDD8-conjugating enzyme Ubc12, hUbc12, UBC-RS2, UBC12

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.2 M NaCl, 1 MM DTT

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: UBE2M (ube2m) (Ubiquitin-Conjugating Enzyme E2M (ube2m))

Autre désignation: UBE2M (ube2m Produits)

Synonymes: DDBDRAFT_0204633 Protein, DDBDRAFT_0238042 Protein, DDB_0204633 Protein, DDB_0238042 Protein, UBC-RS2 Protein, UBC12 Protein, hUbc12 Protein, 2510040H03Rik Protein, Ubc-rs2 Protein, ubiquitin conjugating enzyme E2M Protein, ubiquitin-conjugating enzyme E2M Protein, ubiquitin conjugating enzyme E2 M Protein, NEDD8-conjugating enzyme Protein, ubiquitin conjugating enzyme E2M S homeolog Protein, ube2m Protein, LOC692934 Protein, UBE2M Protein, Ube2m Protein, ube2m.S Protein

Sujet: UBE2M, also known as NEDD8-conjugating enzyme Ubc12, belongs to the ubiquitin-conjugating enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin. Recombinant human UBE2M protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Poids moléculaire: 23.5 kDa (207aa) confirmed by MALDI-TOF

NCBI Accession: NP_003960