MFAP2 Protein (AA 18-183) (His tag)

N° du produit ABIN1098693

Cette protéine Recombinant MFAP2 est exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour MFAP2 Protein (AA 18-183) (His tag) (ABIN1098693)

Antigène: MFAP2 (Microfibrillar Associated Protein 2 (MFAP2))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Pureté: > 85 %

Détail du produit

Attributs du protein: AA 18-183

Purification/Conjugué: Cette MFAP2 protéine est marqué à la His tag.

Séquence: QGQYDL DPLPPFPDHV QYTHYSDQID NPDYYDYQEV TPRPSEEQFQ FQSQQQVQQE VIPAPTPEPG NAELEPTEPG PLDCREEQYP CTRLYSIHRP CKQCLNEVCF YSLRRVYVIN KEICVRTVCA HEELLRADLC RDKFSKCGVM ASSGLCQSVA ASCARSCGSC

Purification: > 85% by SDS-PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 8.0) containing 1M urea, 20 % glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: MFAP2 (Microfibrillar Associated Protein 2 (MFAP2))

Autre désignation: MAGP-1/MFAP2

Sujet: Microfibrillar-associated protein 2, also known as MFAP2, is an O-glycosylated protein secreted to the extracellular space and the extracellular matrix. MFAP2 associates with biglycan and elastin in a ternary complex. It is shown to play a significant role in the support and distensibility of the juxtacanalicular region of these collector channels. It is also reported to inhibit LTB-1 binding to fibrillin-1, stimulate the phosphorylation of Smad2, and thereby mediate the subsequent extracellular deposition of latent TGFbeta. Recombinant human MFAP2, fused to His-tag at N-terminus, was expressed in E. coli.

Poids moléculaire: 21.5 kDa (190aa)

NCBI Accession: NP_002394