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MFAP2 Protein (His tag)

MFAP2 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
N° du produit ABIN1098693
  • Antigène Voir toutes MFAP2 Protéines
    MFAP2 (Microfibrillar Associated Protein 2 (MFAP2))
    Type de proteíne
    Recombinant
    Origine
    • 8
    • 2
    • 1
    • 1
    Humain
    Source
    • 5
    • 3
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette MFAP2 protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Pureté
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product MFAP2 Protéine
  • Commentaires

    Synonyms: Microfibrillar-associated protein 2, Microfibrillar-associated protein 2, MAGP, MAGP-1, MAGP1

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 1 M Urea, 20% glycerol
    Stock
    4 °C
    Stockage commentaire
    Avoid repeated freezing and thawing cycles.
  • Antigène
    MFAP2 (Microfibrillar Associated Protein 2 (MFAP2))
    Autre désignation
    MFAP2 (MFAP2 Produits)
    Synonymes
    MAGP Protein, MAGP-1 Protein, MAGP1 Protein, AI893631 Protein, Magp Protein, Magp1 Protein, microfibril associated protein 2 Protein, microfibrillar-associated protein 2 Protein, MFAP2 Protein, Mfap2 Protein
    Sujet
    Microfibrillar-associated protein 2, also known as MFAP2, is an O-glycosylated protein secreted to the extracellular space and the extracellular matrix. MFAP2 associates with biglycan and elastin in a ternary complex. It is shown to play a significant role in the support and distensibility of the juxtacanalicular region of these collector channels. It is also reported to inhibit LTB-1 binding to fibrillin-1, stimulate the phosphorylation of Smad2, and thereby mediate the subsequent extracellular deposition of latent TGFbeta. Recombinant human MFAP2, fused to His-tag at N-terminus, was expressed in E.coli.
    Poids moléculaire
    21.5 kDa (190aa)
    NCBI Accession
    NP_002394
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