RASSF1 Protein (His tag)

N° du produit ABIN1098704

Détail du produit

Antigène: RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette RASSF1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Pureté: > 85 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: Ras association domain-containing protein 1, 123F2, NORE2A, RASSF1, RDA32, REH3P21

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))

Autre désignation: RASSF1A (RASSF1 Produits)

Synonymes: RASSF1 Protein, zgc:92505 Protein, wu:fc17f02 Protein, zgc:112224 Protein, 123F2 Protein, NORE2A Protein, RASSF1A Protein, RDA32 Protein, REH3P21 Protein, AA536941 Protein, AU044980 Protein, Rassf1A Protein, Rassf1B Protein, Rassf1C Protein, NPR2-like, GATOR1 complex subunit Protein, Ras association (RalGDS/AF-6) domain family 1 Protein, Ras association domain family member 1 Protein, putative rassf1 Protein, Ras association domain family member 1 L homeolog Protein, Ras association (RalGDS/AF-6) domain family member 1 Protein, NPRL2 Protein, rassf1 Protein, RASSF1 Protein, Smp_157340 Protein, rassf1.L Protein, Rassf1 Protein

Sujet: RASSF1A is similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. This protein required for death receptor-dependent apoptosis. Recombinant human RASSF1A protein, fused to His-tag at N-terminus, was expressed in E.coli.

Poids moléculaire: 42.9 kDa (376aa)

NCBI Accession: NP_009113