Retinoic Acid Early Transcript 1E (RAET1E) protein (His tag)
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- Antigène Voir toutes Retinoic Acid Early Transcript 1E (RAET1E) Protéines
- Retinoic Acid Early Transcript 1E (RAET1E)
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- His tag
- Application
- SDS-PAGE (SDS)
- Pureté
- > 90 % by SDS - PAGE
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- Commentaires
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Synonyms: NKG2D ligand 4, bA350J20.7, LETAL, N2DL-4, NKG2DL4, RAET1E2, RL-4, ULBP4
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M UREA, 10% glycerol
- Stock
- 4 °C
- Stockage commentaire
- Avoid repeated freezing and thawing cycles.
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- Antigène
- Retinoic Acid Early Transcript 1E (RAET1E)
- Autre désignation
- RAET1E (RAET1E Produits)
- Synonymes
- LETAL Protein, N2DL-4 Protein, NKG2DL4 Protein, RAET1E2 Protein, RL-4 Protein, ULBP4 Protein, bA350J20.7 Protein, retinoic acid early transcript 1E Protein, RAET1E Protein, Raet1e Protein
- Sujet
- RAET1E belongs to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24.2-q25.3. RAET1E and RAET1G protein differ from other RAET1 proteins in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. This protein functions as a ligand for NKG2D receptor, which is expressed on the surface of several types of immune cells, and is involved in innate adaptive immune responses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Recombinant human RAET1E protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Poids moléculaire
- 24.9 kDa (219aa)
- NCBI Accession
- NP_631904
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