MAFK Protein (His tag)

N° du produit ABIN1098756

Détail du produit

Antigène: MAFK (Transcription Factor MafK (MAFK))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette MAFK protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Pureté: > 85 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: Transcription factor MafK, NFE2U, P18

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: MAFK (Transcription Factor MafK (MAFK))

Autre désignation: MAFK (MAFK Produits)

Synonymes: NFE2U Protein, P18 Protein, AW061068 Protein, NF-E2 Protein, Nfe2u Protein, MAF bZIP transcription factor K Protein, v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian) Protein, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K Protein, Mafk Protein, MAFK Protein, mafk Protein

Sujet: MAFK belongs to the bZIP family and Maf subfamily. Members of the Maf family of basic region/leucine zipper (bZIP) transcription factors affect transcription in either a positive or negative fashion, depending on their particular protein partner and the context of the target promoter. Small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Recombinant human MAFK protein, fused to His-tag at N-terminus, was expressed in E.coli.

Poids moléculaire: 19.7 kDa (176aa)

NCBI Accession: NP_002351