XPA Protein (AA 1-273) (His tag)

N° du produit ABIN1098757

Protéine Recombinant XPA exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour XPA Protein (AA 1-273) (His tag) (ABIN1098757)

Antigène: XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Pureté: > 85 %

Détail du produit

Attributs du protein: AA 1-273

Purification/Conjugué: Cette XPA protéine est marqué à la His tag.

Séquence: MAAADGA LPEAAALEQP AELPASVRAS IERKRQRALM LRQARLAARP YSATAAAATG GMANVKAAPK IIDTGGGFIL EEEEEEEQKI GKVVHQPGPV MEFDYVICEE CGKEFMDSYL MNHFDLPTCD NCRDADDKHK LITKTEAKQE YLLKDCDLEK REPPLKFIVK KNPHHSQWGD MKLYLKLQIV KRSLEVWGSQ EALEEAKEVR QENREKMKQK KFDKKVKELR RAVRSSVWKR ETIVHQHEYG PEENLEDDMY RKTCTMCGHE LTYEKM

Purification: > 85% by SDS-PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Synonyms: DNA repair protein complementing XP-A cells, XP1, XPAC

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M urea, 10 % glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))

Autre désignation: XPA

Sujet: XPA, also known as DNA repair protein complementing XP-A cells, belong to the XPA family. This protein is involved in DNA excision repair. It Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Defects in XPA are a cause of xeroderma pigmentosum complementation group A (XP-A), which is a rare human autosomal recessive disease characterized by solar sensitivity, high predisposition for developing cancers on areas exposed to sunlight and, in some cases, neurological abnormalities. Recombinant human XPA protein, fused to His-tag at N-terminus, was expressed in E. coli.

Poids moléculaire: 33.8 kDa (296aa)

NCBI Accession: NP_000371

Pathways: Réparation de l'ADN