PSMD4/ASF Protein (AA 2-377)

N° du produit ABIN1343997

Détail du produit

Antigène: PSMD4/ASF (Psmd4) (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))

Type de proteíne: Recombinant

Attributs du protein: AA 2-377

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Réactivité croisée: Humain

Attributs du produit: Human angiocidin (aa 2-377) is untagged.

Pureté: >95 % (SDS-PAGE)

niveau d'endotoxine: <0.1EU/μg purified protein (LAL test, Lonza).

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with 100 μL sterile water.

Concentration: Lot specific

Buffer: Lyophilized. Contains PBS.

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C.

Date de péremption: 6 months

Détail du antigène

Antigène: PSMD4/ASF (Psmd4) (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))

Autre désignation: Angiocidin (Psmd4 Produits)

Synonymes: af-1 Protein, mcb1 Protein, pub-r5 Protein, rpn10 Protein, PSMD4 Protein, DDBDRAFT_0202512 Protein, DDBDRAFT_0232981 Protein, DDB_0202512 Protein, DDB_0232981 Protein, AF Protein, AF-1 Protein, ASF Protein, MCB1 Protein, Rpn10 Protein, S5A Protein, pUB-R5 Protein, xrpn10c Protein, Af1 Protein, Mcb1 Protein, angiocidin Protein, im:6912672 Protein, psmd4 Protein, wu:fc68c04 Protein, zgc:110247 Protein, proteasome 26S subunit, non-ATPase 4 Protein, 26S proteasome non-ATPase regulatory subunit 4 Protein, 26s proteasome non-atpase regulatory subunit 4 (26s proteasomeregulatory subunit s5a) Protein, proteasome 26S subunit, non-ATPase 4 L homeolog Protein, proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 Protein, proteasome 26S subunit, non-ATPase 4b Protein, psmd4 Protein, PSMD4 Protein, LOC100194679 Protein, psmD4 Protein, LOC100283637 Protein, Smp_000740.1 Protein, psmd4.L Protein, Psmd4 Protein, psmd4b Protein

Sujet: Angiocidin shows sequence similarity with proteasome components and is also being referred to as 26A proteasome regulatory subunit S5A. Angiocidin shows both matrix and cytoplasmic distribution. It binds to thrombospondin-1 and alpha2beta1 integrin, and it inhibits tumor progression and angiogenesis. Angiocidin is expressed in various types of cancer, such as hepatocellular carcinoma, prostate, lung, bladder, and melanoma cancers.

Poids moléculaire: ~50kDa (SDS-PAGE)

UniProt: P55036

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway