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IL1R1 Protein (AA 21-336) (Fc Tag)

IL1R1 Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % (SDS-PAGE) SDS Active
N° du produit ABIN1344138
  • Antigène Voir toutes IL1R1 Protéines
    IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Attributs du protein
    AA 21-336
    Origine
    • 18
    • 10
    • 9
    Humain
    Source
    • 14
    • 10
    • 4
    • 4
    • 3
    • 2
    HEK-293 Cells
    Purification/Conjugué
    Cette IL1R1 protéine est marqué à la Fc Tag.
    Application
    SDS-PAGE (SDS)
    Specificité
    Binds to human IL-1beta.
     Réactivité croisée
    Humain
    Attributs du produit
    Human IL-1RI (interleukin-1 receptor type I) (aa 21-336) is fused at the C-terminus to the Fc portion of human IgG1.
    Pureté
    >95 % (SDS-PAGE)
    niveau d'endotoxine
    <0.1EU/μg purified protein (LAL test, Lonza).
    Top Product
    Discover our top product IL1R1 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Commentaires

    Blocks IL-1beta activity.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with 50 μL sterile water.
    Concentration
    Lot specific
    Buffer
    Lyophilized. Contains PBS.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    Date de péremption
    6 months
  • Antigène
    IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
    Abstract
    IL1R1 Produits
    Synonymes
    CD121A Protein, D2S1473 Protein, IL-1R-alpha Protein, IL1R Protein, IL1RA Protein, P80 Protein, CD121a Protein, CD121b Protein, IL-iR Protein, Il1r-1 Protein, DER4 Protein, Fit-1 Protein, Ly84 Protein, ST2L Protein, St2 Protein, St2-rs1 Protein, T1 Protein, T1/ST2 Protein, interleukin 1 receptor type 1 Protein, interleukin 1 receptor, type I Protein, interleukin 1 receptor-like 1 Protein, IL1R1 Protein, Il1r1 Protein, Il1rl1 Protein
    Sujet
    IL-1RI is the receptor for interleukin-1alpha (IL-1A), beta (IL-1B) and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappaB. Signaling involves formation of a ternary complex containing IL1RAP, leading the activation of TOLLIP, MYD88 and IRAK1 or IRAK2.
    Poids moléculaire
    ~80kDa (SDS-PAGE)
    UniProt
    P14778
    Pathways
    Signalisation NF-kappaB, Carbohydrate Homeostasis, Cancer Immune Checkpoints
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