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JAG1 Protein (AA 1-1067, Extracellular Domain) (Fc Tag)

JAG1 Origine: Humain Hôte: HEK-293 Cells Recombinant >90 % (SDS-PAGE) SDS Active
N° du produit ABIN1344183
  • Antigène Voir toutes JAG1 Protéines
    JAG1 (Jagged 1 (JAG1))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Attributs du protein
    Extracellular Domain, AA 1-1067
    Origine
    • 15
    • 5
    • 1
    Humain
    Source
    • 7
    • 5
    • 4
    • 3
    • 2
    HEK-293 Cells
    Purification/Conjugué
    Cette JAG1 protéine est marqué à la Fc Tag.
    Application
    SDS-PAGE (SDS)
     Réactivité croisée
    Humain
    Attributs du produit
    Signal peptide and extracellular domain of human Jagged-1 (HJ1, CD339) (aa 1-1067) are fused at the C-terminus to the Fc portion of human IgG1.
    Pureté
    >90 % (SDS-PAGE)
    Stérilité
    0.2 μm filtered
    niveau d'endotoxine
    <0.1EU/μg purified protein (LAL test, Lonza).
    Top Product
    Discover our top product JAG1 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Commentaires

    Inhibits adipogenesis of mesenchymal stem cells (MSCs). Induces Hes-1 in 3T3L-1 cells.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    0.2μm-filtered solution in PBS.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Working aliquots are stable for up to 3 months when stored at -20°C.
    Date de péremption
    3 months
  • Antigène
    JAG1 (Jagged 1 (JAG1))
    Autre désignation
    Jagged-1 (JAG1 Produits)
    Synonymes
    AGS Protein, AHD Protein, AWS Protein, CD339 Protein, HJ1 Protein, JAGL1 Protein, ABE2 Protein, Gsfabe2 Protein, Htu Protein, Ozz Protein, Ser-1 Protein, JAG1 Protein, jag3 Protein, cb243 Protein, jag1 Protein, sb:cb243 Protein, serrateC Protein, jagged1 Protein, serrate Protein, serrate-1 Protein, x-serrate-1 Protein, jagged 1 Protein, jagged 1b Protein, jagged 1a Protein, jagged 1 L homeolog Protein, JAG1 Protein, Jag1 Protein, jag1 Protein, jag1b Protein, jag1a Protein, jag1.L Protein
    Sujet
    Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF).
    Poids moléculaire
    ~150kDa (SDS-PAGE)
    UniProt
    P78504
    Pathways
    Signalisation Notch, Stem Cell Maintenance
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