RPL5 Protein (AA 2-297, full length) (GST tag)

N° du produit ABIN7479215

Détail du produit

Antigène: RPL5 (Ribosomal Protein L5 (RPL5))

Type de proteíne: Recombinant

Attributs du protein: AA 2-297, full length

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette RPL5 protéine est marqué à la GST tag.

Application: ELISA

Séquence: GFVKVVKNKA YFKRYQVKFR RRREGKTDYY ARKRLVIQDK NKYNTPKYRM IVRVTNRDII CQIAYARIEG DMIVCAAYAH ELPKYGVKVG LTNYAAAYCT GLLLARRLLN RFGMDKIYEG QVEVTGDEYN VESIDGQPGA FTCYLDAGLA RTTTGNKVFG ALKGAVDGGL SIPHSTKRFP GYDSESKEFN AEVHRKHIMG QNVADYMRYL MEEDEDAYKK QFSQYIKNSV TPDMMEEMYK KAHAAIRENP VYEKKPKKEV KKKRWNRPKM SLAQKKDRVA QKKASFLRAQ ERAAES

Attributs du produit: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Pureté: 95 %

Information d'application

Commentaires:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Conseil sur la manipulation: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Stock: -20 °C

Stockage commentaire: Store at -20 °C for extended storage, conserve at -20 °C or -80 °C

Détail du antigène

Antigène: RPL5 (Ribosomal Protein L5 (RPL5))

Autre désignation: 60S ribosomal protein L5 protein (RPL5 Produits)

Synonymes: DBA6 Protein, L5 Protein, U21RNA Protein, CG17489 Protein, Dmel\\CG17489 Protein, E-2d Protein, M(2)40B Protein, Rp L5 Protein, Rpl5 Protein, dRPL5 Protein, yip6 Protein, rpl5 Protein, wu:fj02g05 Protein, zgc:86854 Protein, mg:cb01f08 Protein, rpl5l Protein, zgc:56511 Protein, zgc:77176 Protein, ribosomal protein L5 Protein, 60S ribosomal protein L5 Protein, Ribosomal protein L5 Protein, ribosomal protein L5 L homeolog Protein, 50S ribosomal protein L5 Protein, ribosomal protein L5 S homeolog Protein, ribosomal protein L5b Protein, rpl5 Protein, ribosomal protein L5a Protein, Rpl5 Protein, RPL5 Protein, rpl-5 Protein, RpL5 Protein, rpl5.L Protein, rpl5 Protein, rpl5.S Protein, rpl5b Protein, rpl5a Protein

Sujet: Required for rRNA maturation and formation of the 60S ribosomal subunits. This protein binds 5S RNA. Defects in RPL5 are the cause of Diamond-Blackfan anemia type 6 (DBA6) [MIM:612561]. DBA6 is a form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies.

Poids moléculaire: 61.6 kD

UniProt: P46777