PPIA Protein (AA 2-165, full length) (GST tag)

N° du produit ABIN7479292

Détail du produit

Antigène: PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))

Type de proteíne: Recombinant

Attributs du protein: AA 2-165, full length

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PPIA protéine est marqué à la GST tag.

Application: ELISA

Séquence: VNPTVFFDIA VDGEPLGRVS FELFADKVPK TAENFRALST GEKGFGYKGS CFHRIIPGFM CQGGDFTRHN GTGGKSIYGE KFEDENFILK HTGPGILSMA NAGPNTNGSQ FFICTAKTEW LDGKHVVFGK VKEGMNIVEA MERFGSRNGK TSKKITIADC GQLE

Attributs du produit: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Pureté: 90 %

Information d'application

Commentaires:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Conseil sur la manipulation: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Stock: -20 °C

Stockage commentaire: Store at -20 °C for extended storage, conserve at -20 °C or -80 °C

Détail du antigène

Antigène: PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))

Autre désignation: Cyclophilin A protein (PPIA Produits)

Synonymes: Cyp1 Protein, PPIA-2 Protein, fa93g09 Protein, ppia Protein, wu:fa93g09 Protein, wu:fb05e11 Protein, wu:fb13h02 Protein, wu:fb15a05 Protein, CYPA Protein, CypA Protein, Cypa Protein, CYPH Protein, CYCA Protein, CyP-A Protein, MGC75715 Protein, 2700098C05 Protein, Cphn Protein, CyP-18 Protein, MT-ND1 Protein, MTND1 Protein, NADH1 Protein, ND1 Protein, cypA Protein, PPIase A Protein, ppial Protein, wu:fj18g05 Protein, zgc:73102 Protein, zgc:86688 Protein, peptidylprolyl isomerase A Protein, peptidylprolyl isomerase Aa (cyclophilin A) Protein, peptidylprolyl isomerase A (cyclophilin A) L homeolog Protein, cyclophilin A Protein, cyclophilin a Protein, peptidylprolyl isomerase A (cyclophilin A) Protein, peptidylprolyl isomerase Ab (cyclophilin A) Protein, PPIA Protein, ppiaa Protein, ppia.L Protein, Cypa Protein, CNB01230 Protein, CNB01290 Protein, Tc00.1047053506925.300 Protein, Tb11.03.0250 Protein, CYPA Protein, Ppia Protein, ppia Protein, ppiab Protein

Sujet: Cyclophilin A, also called peptidylisomeras A, PPIA, CYPA, and CYPH, was originally characterized for its ability to catalyze the transition between cis­, and trans­, proline residues critical for proper folding of proteins. Cyclophilin is also incorporated into many viruses, including HIV­,1, where it has been speculated to be involved in functions such as viral assembly and infectivity. The immunosuppressive activity of cyclosporins has been correlated with their ability to form complexes with cyclophilins that inhibit calcineurin phosphatase activity and prevent incorporation of cyclophilin into viral particles. The cyclosporin/cyclophilin complex selectively binds and inactivates calcineurin, making it a useful inhibitor for studying calcineurin activity.

Poids moléculaire: 45.3 kD

UniProt: P62937