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PDCD1LG2 Protein (AA 20-219) (His tag)

PDCD1LG2 Origine: Humain Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN1691367
  • Antigène Voir toutes PDCD1LG2 Protéines
    PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 20-219
    Origine
    • 30
    • 12
    • 2
    • 2
    Humain
    Source
    • 26
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Purification/Conjugué
    Cette PDCD1LG2 protéine est marqué à la His tag.
    Fonction
    Recombinant Human PD-L2/B7-DC/CD273 (C-6His)
    Séquence
    LFTVTVPKEL YIIEHGSNVT LECNFDTGSH VNLGAITASL QKVENDTSPH RERATLLEEQ LPLGKASFHI PQVQVRDEGQ YQCIIIYGVA WDYKYLTLKV KASYRKINTH ILKVPETDEV ELTCQATGYP LAEVSWPNVS VPANTSHSRT PEGLYQVTSV LRLKPPPGRN FSCVFWNTHV RELTLASIDL QSQMEPRTHP VDHHHHHH
    Attributs du produit
    Recombinant Human Programmed Cell Death 1 Ligand 2/PDCD1LG2 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Leu20-Pro219) of Human PDCD1LG2 fused with a 6His tag at the C-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    Stérilité
    0.2 μm filtered
    niveau d'endotoxine
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product PDCD1LG2 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Conseil sur la manipulation
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Stock
    4 °C/-20 °C/-80 °C
    Stockage commentaire
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Date de péremption
    3 months
  • Antigène
    PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
    Autre désignation
    PD-L2 (PDCD1LG2 Produits)
    Synonymes
    PDL2 Protein, B7DC Protein, Btdc Protein, CD273 Protein, PD-L2 Protein, PDCD1L2 Protein, bA574F11.2 Protein, B7-DC Protein, F730015O22Rik Protein, programmed cell death 1 ligand 2 Protein, PDCD1LG2 Protein, Pdcd1lg2 Protein
    Sub Type
    Fusionprotein
    Sujet
    Programmed Cell Death 1 Ligand 2 (PDCD1LG2) is a member of the BTN/MOG family. PDCD1LG2 contains one Ig-like C2-type domain and one Ig-like V-type domain. PDCD1LG2 is highly expressed in the heart, placenta, pancreas, lung and liver, it is weakly expressed in the spleen, lymph nodes, and thymus. PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PDCD1LG2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
    Alternative Names: Programmed Cell Death 1 Ligand 2, PD-1 Ligand 2, PD-L2, PDCD1 Ligand 2, Programmed Death Ligand 2, Butyrophilin B7-DC, B7-DC, CD273, PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2
    Poids moléculaire
    23.59 kDa
    UniProt
    Q9BQ51
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