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SGSH Protein (AA 21-502) (His tag)

SGSH Origine: Humain Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN1691380
  • Antigène Voir toutes SGSH Protéines
    SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 21-502
    Origine
    • 4
    • 2
    Humain
    Source
    • 3
    • 1
    • 1
    • 1
    Human Cells
    Purification/Conjugué
    Cette SGSH protéine est marqué à la His tag.
    Fonction
    Recombinant Human N-Sulphoglucosamine Sulphohydrolase/SGSH (C-6His)
    Séquence
    RPRNALLLLA DDGGFESGAY NNSAIATPHL DALARRSLLF RNAFTSVSSC SPSRASLLTG LPQHQNGMYG LHQDVHHFNS FDKVRSLPLL LSQAGVRTGI IGKKHVGPET VYPFDFAYTE ENGSVLQVGR NITRIKLLVR KFLQTQDDRP FFLYVAFHDP HRCGHSQPQY GTFCEKFGNG ESGMGRIPDW TPQAYDPLDV LVPYFVPNTP AARADLAAQY TTVGRMDQGV GLVLQELRDA GVLNDTLVIF TSDNGIPFPS GRTNLYWPGT AEPLLVSSPE HPKRWGQVSE AYVSLLDLTP TILDWFSIPY PSYAIFGSKT IHLTGRSLLP ALEAEPLWAT VFGSQSHHEV TMSYPMRSVQ HRHFRLVHNL NFKMPFPIDQ DFYVSPTFQD LLNRTTAGQP TGWYKDLRHY YYRARWELYD RSRDPHETQN LATDPRFAQL LEMLRDQLAK WQWETHDPWV CAPDGVLEEK LSPQCQPLHN ELVDHHHHHH
    Attributs du produit
    Recombinant Human N-Sulphoglucosamine Sulphohydrolase/SGSH is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Arg21-Leu502) of Human SGSH fused with a 6His tag at the C-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    Stérilité
    0.2 μm filtered
    niveau d'endotoxine
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product SGSH Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,1 mM GaCl2,10 % Glycerol, pH 7.5.
    Conseil sur la manipulation
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Stock
    -80 °C
    Stockage commentaire
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))
    Abstract
    SGSH Produits
    Synonymes
    HSS Protein, MPS3A Protein, SFMD Protein, 4632406A19Rik Protein, N-sulfoglucosamine sulfohydrolase Protein, N-sulfoglucosamine sulfohydrolase (sulfamidase) Protein, SGSH Protein, Sgsh Protein
    Sub Type
    Fusionprotein
    Sujet
    N-Sulphoglucosamine Sulphohydrolase (SGSH) is an important member of the sulfatase family which is involved in the degradation of heparin sulfate. SGSH binds one calcium ion per subunit as a cofactor. SGSH catalyzes N-sulfo-D-glucosamine and H2O to D-glucosamine and sulfate. SGSH deficiency is result in mucopolysaccharidosis type 3A (MPS3A), a recessive lysosomal storage disease characterized by neurological dysfunction but relatively mild somatic manifestations.
    Alternative Names: N-Sulphoglucosamine Sulphohydrolase, Sulfoglucosamine Sulfamidase, Sulphamidase, SGSH, HSS
    Poids moléculaire
    55.72 kDa
    UniProt
    P51688
    Pathways
    Glycosaminoglycan Metabolic Process
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