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CD99 Protein (CD99) (AA 23-122) (Fc Tag)

CD99 Origine: Humain Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN1691518
  • Antigène Voir toutes CD99 Protéines
    CD99
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 23-122
    Origine
    • 17
    • 4
    • 3
    • 1
    Humain
    Source
    • 10
    • 6
    • 3
    • 3
    • 1
    • 1
    Human Cells
    Purification/Conjugué
    Cette CD99 protéine est marqué à la Fc Tag.
    Fonction
    Recombinant Human CD99/MIC2 (C-Fc)
    Séquence
    DGGFDLSDAL PDNENKKPTA IPKKPSAGDD FDLGDAVVDG ENDDPRPPNP PKPMPNPNPN HPSSSGSFSD ADLADGVSGG EGKGGSDGGG SHRKEGEEAD VDDIEGRMDE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRE EMTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG K
    Attributs du produit

    Recombinant Human CD99/MIC2 (C-Fc)

    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    Stérilité
    0.2 μm filtered
    niveau d'endotoxine
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product CD99 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Conseil sur la manipulation
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Stock
    4 °C/-20 °C/-80 °C
    Stockage commentaire
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Antigène
    CD99
    Autre désignation
    CD99 (CD99 Produits)
    Synonymes
    1110061M03Rik Protein, 2410026K10Rik Protein, D4 Protein, Pilr-l Protein, pilr-1 Protein, HBA71 Protein, MIC2 Protein, MIC2X Protein, MIC2Y Protein, MSK5X Protein, CD99 antigen Protein, CD99 molecule (Xg blood group) Protein, CD99 molecule Protein, Cd99 Protein, CD99 Protein
    Classe de substances
    Viral Protein
    Sujet
    Recombinant Human CD99/MIC2/MIC2X/MIC2Y is produced by our mammalian expression system. The target protein is expressed with sequence (Asp23-Asp122) of Human CD99 fused with a FC tag at the C-terminus.
    CD99 is a type I transmembrane glycoprotein and the founding member of the CD99 family of molecules. The extracellular domain of CD99 contains no identifiable motifs, its cytoplasmic region, although short, does have signal transduction capability. Cells known to express CD99 include fibroblasts, neutrophils, T cells, double positive thymocytes, CD34+ stem cells, monocytes and endothelial cells. Two types of CD99 isoforms have been classified. Native human CD99 is referred to as the long, or type I isoform. The best studied type II isoform shows an Asp-Gly substitution for the C terminal 27 AAs. The type I and II isoforms have distinctive signal transduction pathways (FAKsrc for type I PI3K plus srcERK1/2 for type II), and mediate clearly different biological outcomes. Homophilic interaction between CD99 on the neutrophil and CD99 on the endothelial cell regulates the transendothelial migration of neutrophils during inflammation. Human CD99 has 48 % aa sequence identity to mouse CD99.
    Poids moléculaire
    37.2 kDa
    UniProt
    P14209
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