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LTBR Protein (AA 28-218) (Fc Tag)

LTBR Origine: Souris Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN1691786
  • Antigène Voir toutes LTBR Protéines
    LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 28-218
    Origine
    • 15
    • 6
    • 2
    Souris
    Source
    • 8
    • 6
    • 6
    • 1
    • 1
    • 1
    Human Cells
    Purification/Conjugué
    Cette LTBR protéine est marqué à la Fc Tag.
    Fonction
    Recombinant Mouse Lymphotoxin β Receptor/LTBR/TNFRSF3/TNFRrp (C-Fc)
    Séquence
    SQPQLVPPYR IENQTCWDQD KEYYEPMHDV CCSRCPPGEF VFAVCSRSQD TVCKTCPHNS YNEHWNHLST CQLCRPCDIV LGFEEVAPCT SDRKAECRCQ PGMSCVYLDN ECVHCEEERL VLCQPGTEAE VTDEIMDTDV NCVPCKPGHF QNTSSPRARC QPHTRCEIQG LVEAAPGTSY SDTICKNPPE PVDDIEGRMD EPKSCDKTHT CPPCPAPELL GGPSVFLFPP KPKDTLMISR TPEVTCVVVD VSHEDPEVKF NWYVDGVEVH NAKTKPREEQ YNSTYRVVSV LTVLHQDWLN GKEYKCKVSN KALPAPIEKT ISKAKGQPRE PQVYTLPPSR EEMTKNQVSL TCLVKGFYPS DIAVEWESNG QPENNYKTTP PVLDSDGSFF LYSKLTVDKS RWQQGNVFSC SVMHEALHNH YTQKSLSLSP GK
    Attributs du produit
    Recombinant Mouse Tumor necrosis factor receptor superfamily member 3/TNFRSF3 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ser28-Pro218) of Mouse TNFRSF3 fused with a FC tag at the C-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    Stérilité
    0.2 μm filtered
    niveau d'endotoxine
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product LTBR Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Conseil sur la manipulation
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Stock
    4 °C/-20 °C/-80 °C
    Stockage commentaire
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Date de péremption
    5 months
  • Antigène
    LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))
    Autre désignation
    TNFRSF3 (LTBR Produits)
    Synonymes
    AI256028 Protein, CD18 Protein, LTbetaR Protein, Ltar Protein, TNF-R-III Protein, TNFCR Protein, TNFR-RP Protein, TNFR2-RP Protein, TNFRrp Protein, Tnfbr Protein, Tnfrsf3 Protein, D12S370 Protein, LT-BETA-R Protein, TNFR3 Protein, TNFRSF3 Protein, lymphotoxin beta receptor Protein, lymphotoxin B receptor Protein, Ltbr Protein, LTBR Protein
    Sub Type
    Fusionprotein
    Sujet
    It is a single-pass type I membrane protein and contains 4 TNFR-Cys repeats. The protein is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein is the receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. It promotes apoptosis via TRAF3 and TRAF5 and may play a role in the development of lymphoid organs. The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and transformed cells. Activation of the encoded protein can trigger apoptosis. Not only does the TNFRSF3 help trigger apoptosis, it can lead to the release of the cytokine interleukin 8. Overexpression of TNFRSF3 in HEK293 cells increases IL-8 promoter activity and leads to IL-8 release. TNFRSF3 is also essential for development and organization of the secondary lymphoid organs and chemokine release.
    Alternative Names: Tumor necrosis factor receptor superfamily member 3 ,Lymphotoxin-beta receptor ,Ltbr, Tnfcr, Tnfrsf3
    Poids moléculaire
    48.7 kDa
    UniProt
    P50284
    Pathways
    Signalisation NF-kappaB
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