TRIM Protein (AA 29-186) (His tag)

N° du produit ABIN1691981

Détail du produit

Antigène: TRIM (TRAT1) (T Cell Receptor Associated Transmembrane Adaptor 1 (TRAT1))

Type de proteíne: Recombinant

Attributs du protein: AA 29-186

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette TRIM protéine est marqué à la His tag.

Fonction: Recombinant Human T Cell Receptor Interacting Molecule/TRIM/TCRIM/TRAT1 (C-6His)

Séquence: MNISHYVEKQ RQDKMYSYSS DHTRVDEYYI EDTPIYGNLD DMISEPMDEN CYEQMKARPE KSVNKMQEAT PSAQATNETQ MCYASLDHSV KGKRRKPRKQ NTHFSDKDGD EQLHAIDASV SKTTLVDSFS PESQAVEENI HDDPIRLFGL IRAKREPINL EHHHHHH

Attributs du produit: Recombinant Human T-Cell Receptor-Associated Transmembrane Adapter 1/TRAT1 is produced with our E. coli expression system. The target protein is expressed with sequence (Asn29-Asn186) of Human TRAT1 fused with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl,10 % Glycerol, pH 7.4.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: -80 °C

Stockage commentaire: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: TRIM (TRAT1) (T Cell Receptor Associated Transmembrane Adaptor 1 (TRAT1))

Autre désignation: TRAT1 (TRAT1 Produits)

Synonymes: TCRIM Protein, TRIM Protein, C030046M14Rik Protein, Tcrim Protein, Trim Protein, T cell receptor associated transmembrane adaptor 1 Protein, T-cell receptor associated transmembrane adaptor 1 Protein, TRAT1 Protein, Trat1 Protein

Sub Type: Fusionprotein

Sujet: T-Cell Receptor-Associated Transmembrane Adapter 1 (TRAT1) is a single-pass type III membrane protein. TRAT1 exists as a disulfide-linked homodimer and is strongly expressed in the thymus, and to a lesser extent in the spleen, lymph node, and peripheral blood lymphocytes. TRAT1 is phosphorylated on tyrosines by LCK or FYN upon TCR activation. Its function is to stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.
Alternative Names: T-Cell Receptor-Associated Transmembrane Adapter 1, T-Cell Receptor-Interacting Molecule, TRIM, pp29/30, TRAT1, TCRIM, HSPC062

Poids moléculaire: 19.4 kDa

UniProt: Q6PIZ9

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway