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NCR3 Protein (AA 19-138) (Fc Tag)

NCR3 Origine: Humain Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN1692293
  • Antigène Voir toutes NCR3 Protéines
    NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 19-138
    Origine
    • 22
    • 2
    • 1
    • 1
    • 1
    Humain
    Source
    • 13
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Purification/Conjugué
    Cette NCR3 protéine est marqué à la Fc Tag.
    Fonction
    Recombinant Human NCR3/NKp30/CD337 (C-Fc)
    Séquence
    LWVSQPPEIR TLEGSSAFLP CSFNASQGRL AIGSVTWFRD EVVPGKEVRN GTPEFRGRLA PLASSRFLHD HQAELHIRDV RGHDASIYVC RVEVLGLGVG TGNGTRLVVE KEHPQLGAGT VDDIEGRMDE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRE EMTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG K
    Attributs du produit

    Recombinant Human NCR3/NKp30/CD337 (C-Fc)

    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    Stérilité
    0.2 μm filtered
    niveau d'endotoxine
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product NCR3 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Conseil sur la manipulation
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Stock
    4 °C/-20 °C/-80 °C
    Stockage commentaire
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Antigène
    NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
    Autre désignation
    Natural Cytotoxicity Triggering Receptor 3/NCR3 (NCR3 Produits)
    Synonymes
    MGC133750 Protein, 1C7 Protein, CD337 Protein, LY117 Protein, MALS Protein, NKp30 Protein, Nkp30 Protein, natural cytotoxicity triggering receptor 3 Protein, NCR3 Protein, Ncr3 Protein
    Sujet
    Recombinant Human Natural Cytotoxicity Triggering Receptor 3/NCR3 is produced with our HEK293 expression system. The target protein is expressed with sequence (Leu19 -Thr138) of Human NCR3 fused with a FC tag at the C-terminus.
    Natural Cytotoxicity Triggering Receptor 3 (NCR3) along with NKp44 and NKp46 constitute a group of receptors termed 'Natural Cytotoxicity Receptors'. They play a major role in triggering NK-mediated killing of most tumor cells lines. NKp30 is a type I transmembrane protein having a single extracellular V-like immunoglobulin domain. NKp30 is selectively expressed both in resting and activated human NK cells. In addition, NKp30 is also involved in NK-mediated induction of dendritic cell (DC) maturation. It has been demonstrated that NK cell activation signaling specifically induces lytic activity against several tumor cell types and synthesis of new NF-κB dependent proteins during the initiation of cytotoxicity.
    Poids moléculaire
    40.2 kDa
    UniProt
    O14931
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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