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ACVR2A Protein (AA 20-134) (Fc Tag,His tag)

ACVR2A Origine: Humain Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN1880618
  • Antigène Voir toutes ACVR2A Protéines
    ACVR2A (Activin A Receptor, Type IIA (ACVR2A))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 20-134
    Origine
    • 11
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human Cells
    Purification/Conjugué
    Cette ACVR2A protéine est marqué à la Fc Tag,His tag.
    Fonction
    Recombinant Human Activin Receptor 2A/Activin RIIA/ACVR2A (C-Fc-6His)
    Séquence
    AILGRSETQE CLFFNANWEK DRTNQTGVEP CYGDKDKRRH CFATWKNISG SIEIVKQGCW LDDINCYDRT DCVEKKDSPE VYFCCCEGNM CNEKFSYFPE MEVTQPTSNP VTPKPVDDIE GRMDEPKSCD KTHTCPPCPA PELLGGPSVF LFPPKPKDTL MISRTPEVTC VVVDVSHEDP EVKFNWYVDG VEVHNAKTKP REEQYNSTYR VVSVLTVLHQ DWLNGKEYKC KVSNKALPAP IEKTISKAKG QPREPQVYTL PPSREEMTKN QVSLTCLVKG FYPSDIAVEW ESNGQPENNY KTTPPVLDSD GSFFLYSKLT VDKSRWQQGN VFSCSVMHEA LHNHYTQKSL SLSPGKHHHH HH
    Attributs du produit
    Recombinant Human Activin Receptor Type-2A/Activin RIIA is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ala20-Pro134) of Human Activin RIIA fused with a FC-6His tag at the C-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    Stérilité
    0.2 μm filtered
    niveau d'endotoxine
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product ACVR2A Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Conseil sur la manipulation
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Stock
    4 °C/-20 °C/-80 °C
    Stockage commentaire
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Date de péremption
    3 months
  • Antigène
    ACVR2A (Activin A Receptor, Type IIA (ACVR2A))
    Autre désignation
    Activin Receptor Type-2A/Activin RIIA (ACVR2A Produits)
    Synonymes
    ACVR2 Protein, ACVR2A Protein, XSTK9 Protein, actrii Protein, acvr2 Protein, ACTRII Protein, Acvr2 Protein, rActR-II Protein, actr2a Protein, acvr2a Protein, wu:fa02e10 Protein, ActrIIa Protein, TactrII Protein, activin A receptor type 2A Protein, activin A receptor type 2A L homeolog Protein, activin A receptor type 2Aa Protein, activin receptor IIA Protein, ACVR2A Protein, acvr2a Protein, Acvr2a Protein, acvr2a.L Protein, acvr2aa Protein
    Sub Type
    Fusionprotein
    Sujet
    Activin Receptor Type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.
    Alternative Names: Activin Receptor Type-2A, Activin Receptor Type IIA, ACTR-IIA, ACTRIIA, ACVR2A, ACVR2
    Poids moléculaire
    41.2 kDa
    UniProt
    P27037
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