IFNA4 Protein (AA 24-189) (His tag)

N° du produit ABIN1880639

Détail du produit

Antigène: IFNA4 (IFNa4) (Interferon, alpha 4 (IFNa4))

Type de proteíne: Recombinant

Attributs du protein: AA 24-189

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette IFNA4 protéine est marqué à la His tag.

Fonction: Recombinant Human Interferon α-4/IFNA4 (C-6His)

Séquence: CDLPQTHSLG NRRALILLAQ MGRISHFSCL KDRHDFGFPE EEFDGHQFQK TQAISVLHEM IQQTFNLFST EDSSAAWEQS LLEKFSTELY QQLNDLEACV IQEVGVEETP LMNEDSILAV RKYFQRITLY LTEKKYSPCA WEVVRAEIMR SLSFSTNLQK RLRRKDVDHH HHHH

Attributs du produit: Recombinant Human Interferon alpha-4/IFNA4 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Cys24-Asp189) of Human IFNA4 fused with a polyhistidine tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.2.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 3 months

Détail du antigène

Antigène: IFNA4 (IFNa4) (Interferon, alpha 4 (IFNa4))

Autre désignation: Interferon alpha-4/IFNA4 (IFNa4 Produits)

Synonymes: IFN-alpha4a Protein, INFA4 Protein, Ifa4 Protein, interferon alpha 4 Protein, interferon, alpha 4 Protein, interferon-alpha-4 Protein, IFNA4 Protein, Ifna4 Protein, LOC100052921 Protein

Sub Type: Fusionprotein

Sujet: Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. They are typically divided among three IFN classes: Type I, Type II and Type III. IFNA4 is a secreted protein and produced by macrophages. Two variants of IFNA4 (IFNA4a and IFNA4b) are known, which differ from each other by changes in their coding regions at nucleotide positions 220 and 410 .
Alternative Names: Interferon alpha-4(IFNA4), also known as Interferon alpha-4B, Interferon alpha-76 and Interferon alpha-M1, belongs to the alpha/beta interferon family.

Poids moléculaire: 20.4 kDa

UniProt: P05014

Pathways: Signalistation JAK/STAT, Hepatitis C