CFHR5 Protein (AA 19-569) (His tag)

N° du produit ABIN1880676

Détail du produit

Antigène: CFHR5 (Complement Factor H-Related 5 (CFHR5))

Type de proteíne: Recombinant

Attributs du protein: AA 19-569

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette CFHR5 protéine est marqué à la His tag.

Fonction: Recombinant Human Complement Factor H-related 5/CFHR5 (C-6His)

Séquence: EGTLCDFPKI HHGFLYDEED YNPFSQVPTG EVFYYSCEYN FVSPSKSFWT RITCTEEGWS PTPKCLRMCS FPFVKNGHSE SSGLIHLEGD TVQIICNTGY SLQNNEKNIS CVERGWSTPP ICSFTKGECH VPILEANVDA QPKKESYKVG DVLKFSCRKN LIRVGSDSVQ CYQFGWSPNF PTCKGQVRSC GPPPQLSNGE VKEIRKEEYG HNEVVEYDCN PNFIINGPKK IQCVDGEWTT LPTCVEQVKT CGYIPELEYG YVQPSVPPYQ HGVSVEVNCR NEYAMIGNNM ITCINGIWTE LPMCVATHQL KRCKIAGVNI KTLLKLSGKE FNHNSRIRYR CSDIFRYRHS VCINGKWNPE VDCTEKREQF CPPPPQIPNA QNMTTTVNYQ DGEKVAVLCK ENYLLPEAKE IVCKDGRWQS LPRCVESTAY CGPPPSINNG DTTSFPLSVY PPGSTVTYRC QSFYKLQGSV TVTCRNKQWS EPPRCLDPCV VSEENMNKNN IQLKWRNDGK LYAKTGDAVE FQCKFPHKAM ISSPPFRAIC QEGKFEYPIC EVDHHHHHH

Attributs du produit: Recombinant Human Complement Factor H-related 5/CFHR5 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Glu19-Glu569) of Human CFHR5 fused with a polyhistidine tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 3 months

Détail du antigène

Antigène: CFHR5 (Complement Factor H-Related 5 (CFHR5))

Autre désignation: Complement Factor H-Related 5/CFHR5 (CFHR5 Produits)

Synonymes: CFHL5 Protein, CFHR5D Protein, FHR-5 Protein, FHR5 Protein, complement factor H related 5 Protein, CFHR5 Protein

Sub Type: Fusionprotein

Sujet: Complement factor H-related protein 5(FHR-5 for short), is a secreted protein which contains 9 Sushi (CCP/SCR) domains. It is expressed by the liver and secreted in plasma. The pattern of the deposits is similar to other complement components, suggesting that FHR-5 may play a role in complement activation and regulation. Defects in CFHR5 have been found in patients with atypical hemolytic uremic syndrome and may contribute to the disease. In contrast to typical hemolytic uremic syndrome, atypical forms have a poorer prognosis, with higher death rates and frequent progression to end-stage renal disease.
Alternative Names:

Poids moléculaire: 63.5 kDa

UniProt: Q9BXR6