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TRIM5 Protein (AA 1-248) (His tag)

TRIM5 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN1945366
  • Antigène Voir toutes TRIM5 Protéines
    TRIM5 (Tripartite Motif Containing 5 (TRIM5))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-248
    Origine
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 14
    • 4
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette TRIM5 protéine est marqué à la His tag.
    Fonction
    Recombinant Human Tripartite Motif-Containing Protein 5/TRIM5/RNF88 (N-6His)
    Séquence
    MGSSHHHHHH SSGLVPRGSH MASGILVNVK EEVTCPICLE LLTQPLSLDC GHSFCQACLT ANHKKSMLDK GESSCPVCRI SYQPENIRPN RHVANIVEKL REVKLSPEGQ KVDHCARHGE KLLLFCQEDG KVICWLCERS QEHRGHHTFL TEEVAREYQV KLQAALEMLR QKQQEAEELE ADIREEKASW KTQIQYDKTN VLADFEQLRD ILDWEESNEL QNLEKEEEDI LKSLTNSETE MVQQTQSLRE LISDLEHRLQ GSVMELLQ
    Attributs du produit
    Recombinant Human TRIM5 is produced by our E. coli expression system. The target protein is expressed with sequence (AA 1-248) of Human TRIM5 fused with a 6His tag at the N-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    Stérilité
    0.2 μm filtered
    niveau d'endotoxine
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product TRIM5 Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Conseil sur la manipulation
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Stock
    -80 °C
    Stockage commentaire
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    TRIM5 (Tripartite Motif Containing 5 (TRIM5))
    Autre désignation
    Tripartite Motif-Containing Protein 5 (TRIM5 Produits)
    Synonymes
    TRIM5 Protein, RNF88 Protein, TRIM5alpha Protein, EG667823 Protein, Gm8833 Protein, RGD1304579 Protein, tripartite motif containing 5 Protein, tripartite motif-containing 5 Protein, TRIM5 Protein, Trim5 Protein
    Sujet
    Tripartite motif-containing Motif 5 is a protein that in humans is encoded by the TRIM5 gene.It is a 493 amino acids protein that belongs to the TRIM/RBCC family.It contains 1 B box-type zinc finger, 1 B30.2/SPRY domain and 1 RING-type zinc finger. TRIM5 present in the cytoplasm recognizes motifs within the capsid proteins and interferes with the uncoating process, therefore preventing successful reverse transcription and transport to the nucleus of the viral genome. The exact mechanism of action has not been shown conclusively, but capsid protein from restricted viruses is removed by proteasome-dependent degradation
    Poids moléculaire
    30.8 kDa
    UniProt
    Q9C035
    Pathways
    Activation of Innate immune Response
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