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PFKFB1 Protein (AA 2-471) (His tag)

PFKFB1 Origine: Humain Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN1945453
  • Antigène Voir toutes PFKFB1 Protéines
    PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 2-471
    Origine
    • 7
    • 1
    • 1
    • 1
    Humain
    Source
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human Cells
    Purification/Conjugué
    Cette PFKFB1 protéine est marqué à la His tag.
    Fonction
    Recombinant Human Fructose-2,6-Bisphosphatase 1/PFKFB1/PFK/FBPase 1 (C-6His)
    Séquence
    SPEMGELTQT RLQKIWIPHS SGSSRLQRRR GSSIPQFTNS PTMVIMVGLP ARGKTYISTK LTRYLNWIGT PTKVFNLGQY RREAVSYKNY EFFLPDNMEA LQIRKQCALA ALKDVHNYLS HEEGHVAVFD ATNTTRERRS LILQFAKEHG YKVFFIESIC NDPGIIAENI RQVKLGSPDY IDCDREKVLE DFLKRIECYE VNYQPLDEEL DSHLSYIKIF DVGTRYMVNR VQDHIQSRTV YYLMNIHVTP RSIYLCRHGE SELNIRGRIG GDSGLSVRGK QYAYALANFI QSQGISSLKV WTSHMKRTIQ TAEALGVPYE QWKALNEIDA GVCEEMTYEE IQEHYPEEFA LRDQDKYRYR YPKGESYEDL VQRLEPVIME LERQENVLVI CHQAVMRCLL AYFLDKSSDE LPYLKCPLHT VLKLTPVAYG CKVESIYLNV EAVNTHREKP ENVDITREPE EALDTVPAHY VDHHHHHH
    Attributs du produit
    Recombinant Human PFKFB1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (AA 2-471) of Human PFKFB1 fused with a polyhistidine tag at the C-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    Stérilité
    0.2 μm filtered
    niveau d'endotoxine
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product PFKFB1 Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Conseil sur la manipulation
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Stock
    -80 °C
    Stockage commentaire
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))
    Autre désignation
    PFKFB1 (PFKFB1 Produits)
    Synonymes
    zgc:55328 Protein, wu:fi11h10 Protein, PFKFB1 Protein, F6PK Protein, HL2K Protein, PFRX Protein, Pfkfb01 Protein, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 Protein, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 S homeolog Protein, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 Protein, pfkfb1 Protein, PFKFB1 Protein, pfkfb1.S Protein, LOC100475853 Protein, Pfkfb1 Protein
    Sujet
    6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. It belongs to the phosphoglycerate mutase family. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.
    Poids moléculaire
    55.6 kDa
    UniProt
    P16118
    Pathways
    Regulation of Carbohydrate Metabolic Process
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