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CYP21A2 Protein (AA 1-495) (GST tag)

CYP21A2 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
N° du produit ABIN1989609
  • Antigène Voir toutes CYP21A2 Protéines
    CYP21A2 (Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-495
    Origine
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 8
    • 5
    • 2
    • 1
    Wheat germ
    Purification/Conjugué
    Cette CYP21A2 protéine est marqué à la GST tag.
    Application
    Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)
    Fonction
    CYP21A2 (Human) Recombinant Protein (P01)
    Séquence
    MLLLGLLLLL PLLAGARLLW NWWKLRSLHL PPLAPGFLHL LQPDLPIYLL GLTQKFGPIY RLHLGLQDVV VLNSKRTIEE AMVKKWADFA GRPEPLTYKL VSRNYPDLSL GDYSLLWKAH KKLTRSALLL GIRDSMEPVV EQLTQEFCER MRAQPGTPVA IEEEFSLLTC SIICYLTFGD KIKDDNLMPA YYKCIQEVLK TWSHWSIQIV DVIPFLRFFP NPGLRRLKQA IEKRDHIVEM QLRQHKESLV AGQWRDMMDY MLQGVAQPSM EEGSGQLLEG HVHMAAVDLL IGGTETTANT LSWAVVFLLH HPEIQQRLQE ELDHELGPGA SSSRVPYKDR ARLPLLNATI AEVLRLRPVV PLALPHRTTR PSSISGYDIP EGTVIIPNLQ GAHLDETVWE RPHEFWPDRF LEPGKNSRAL AFGCGARVCL GEPLARLELF VVLTRLLQAF TLLPSGDALP SLQPLPHCSV ILKMQPFQVR LQPRGMGAHS PGQSQ
    Attributs du produit
    Human CYP21A2 full-length ORF (BAG37212.1, 1 a.a. - 495 a.a.) recombinant protein with GST tag at N-terminal.
    Purification
    in vitro wheat germ expression system
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
    Conseil sur la manipulation
    Aliquot to avoid repeated freezing and thawing.
    Stock
    -80 °C
    Stockage commentaire
    Best use within three months from the date of receipt of this protein.
  • Antigène
    CYP21A2 (Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2))
    Autre désignation
    CYP21A2 (CYP21A2 Produits)
    Synonymes
    CA21H Protein, CAH1 Protein, CPS1 Protein, CYP21 Protein, CYP21B Protein, P450c21B Protein, 21-OH Protein, 21OH Protein, 21OHA Protein, 21OHB Protein, CYP21OH-A Protein, Cyp21 Protein, Cyp21-ps1 Protein, Cyp21B Protein, Cyp21a2-ps Protein, Cyp21a2ps Protein, Oh21-1 Protein, Oh21-2 Protein, CYP21A Protein, 21-OHase Protein, cytochrome P450 family 21 subfamily A member 2 Protein, cytochrome P450, family 21, subfamily a, polypeptide 1 Protein, cytochrome P450c21 Protein, cytochrome P450, family 21, subfamily A, polypepide 2 Protein, cytochrome P450, family 21, subfamily A, polypeptide 2 Protein, steroid 21-hydroxylase-like Protein, CYP21A2 Protein, Cyp21a1 Protein, LOC101094596 Protein
    Sujet
    Synonyms: CA21H,CAH1,CPS1,CYP21,CYP21B,MGC150536,MGC150537,P450c21B
    Gene Description: cytochrome P450, family 21, subfamily A, polypeptide 2
    Gene Name: CYP21A2
    Gene Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene, gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene.
    GenBank: AK314651.1, BAG37212.1
    Poids moléculaire
    80.85 kDa (theoreatical)
    ID gène
    1589
    Pathways
    Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
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