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PCSK1 Protein (AA 1-753) (GST tag)
PCSK1
Origine: Humain
Hôte: Wheat germ
Recombinant
WB, ELISA, AP, AA
N° du produit ABIN1989721
Détail du produit
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Antigène
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PCSK1
(Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1))
Type de proteíne
Recombinant
Attributs du protein
AA 1-753
Origine
Toutes les origines à travers PCSK1 Protéines
Humain
Source
Toutes les sources à travers PCSK1 Protéines
Wheat germ
Purification/Conjugué
Cette PCSK1 protéine est marqué à la GST tag.
Application
Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)
Fonction
PCSK1 (Human) Recombinant Protein (P01)
Séquence
MERRAWSLQC TAFVLFCAWC ALNSAKAKRQ FVNEWAAEIP GGPEAASAIA EELGYDLLGQ IGSLENHYLF KHKNHPRRSR RSAFHITKRL SDDDRVIWAE QQYEKERSKR SALRDSALNL FNDPMWNQQW YLQDTRMTAA LPKLDLHVIP VWQKGITGKG VVITVLDDGL EWNHTDIYAN YDPEASYDFN DNDHDPFPRY DPTNENKHGT RCAGEIAMQA NNHKCGVGVA YNSKVGGIRM LDGIVTDAIE ASSIGFNPGH VDIYSASWGP NDDGKTVEGP GRLAQKAFEY GVKQGRQGKG SIFVWASGNG GRQGDNCDCD GYTDSIYTIS ISSASQQGLS PWYAEKCSST LATSYSSGDY TDQRITSADL HNDCTETHTG TSASAPLAAG IFALALEANP NLTWRDMQHL VVWTSEYDPL ANNPGWKKNG AGLMVNSRFG FGLLNAKALV DLADPRTWRS VPEKKECVVK DNDFEPRALK ANGEVIIEIP TRACEGQENA IKSLEHVQFE ATIEYSRRGD LHVTLTSAAG TSTVLLAERE RDTSPNGFKN WDFMSVHTWG ENPIGTWTLR ITDMSGRIQN EGRIVNWKLI LHGTSSQPEH MKQPRVYTSY NTVQNDRRGV EKMVDPGEEQ PTQENPKENT LVSKSPSSSS VGGRRDELEE GAPSQAMLRL LQSAFSKNSP PKQSPKKSPS AKLNIPYENF YEALEKLNKP SQLKDSEDSL YNDYVDVFYN TKPYKHRDDR LLQALVDILN EEN
Attributs du produit
Human PCSK1 full-length ORF (NP_000430.3, 1 a.a. - 753 a.a.) recombinant protein with GST tag at N-terminal.
Purification
in vitro wheat germ expression system
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
Conseil sur la manipulation
Aliquot to avoid repeated freezing and thawing.
Stock
-80 °C
Stockage commentaire
Best use within three months from the date of receipt of this protein.
Détail du antigène
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Antigène
PCSK1
(Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1))
Autre désignation
PCSK1 (PCSK1 Produits )
Synonymes
BMIQ12 Protein, NEC1 Protein, PC1 Protein, PC3 Protein, SPC3 Protein, Nec-1 Protein, Nec1 Protein, Phpp-1 Protein, BDP Protein, PC1/3 Protein, proprotein convertase subtilisin/kexin type 1 Protein, prohormone convertase 1 Protein, PCSK1 Protein, Pcsk1 Protein, pcsk1 Protein, PC1B Protein
Sujet
Synonyms: BMIQ12,NEC1,PC1,PC3,SPC3 Gene Description: proprotein convertase subtilisin/kexin type 1 Gene Name: PCSK1 Gene Summary: The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a type I proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. It is also known to cleave proopiomelanocortin, prorenin, proenkephalin, prodynorphin, prosomatostatin and progastrin. Mutations in this gene are thought to cause obesity. This encoded protein is associated with carcinoid tumors. The use of alternate polyadenylation sites has been found for this gene. Multiple alternatively spliced transcript variants have been described for this gene but their full length nature is not known.
Poids moléculaire
110.6 kDa (theoreatical)
ID gène
5122
NCBI Accession
NM_000439
Pathways
Peptide Hormone Metabolism
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