GM-CSF Protein (AA 18-141)

N° du produit ABIN2017886

Détail du produit

Antigène: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Type de proteíne: Recombinant

Activité biologique: Active

Attributs du protein: AA 18-141

Origine: Souris

Source: CHO Cells

Attributs du produit: ED50 < 0.05 ng/mL, measured in a cell proliferation assay using mouse FDC-P1 cells, corresponding to a specific activity of >2 x 10^7 units/mg.

Pureté: > 95 % as analyzed by SDS-PAGE and HPLC.

niveau d'endotoxine: < 0.2 EU/μg, determined by LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstituted in ddH2O or PBS at 100 μg/mL.

Buffer: Lyophilized after extensive dialysis against PBS.

Stock: -80 °C

Stockage commentaire: Lyophilized recombinant murine Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rmGM-CSF should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

Date de péremption: 6 months

Détail du antigène

Antigène: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Autre désignation: GM-CSF (CSF2 Produits)

Synonymes: GMCSF Protein, GM-CSF Protein, CSF2 Protein, Csfgm Protein, Gm-CSf Protein, MGI-IGM Protein, Gm-csf Protein, Gmcsf Protein, CSF Protein, colony stimulating factor 2 Protein, colony stimulating factor 2 (granulocyte-macrophage) Protein, CSF2 Protein, Csf2 Protein

Sujet: Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine or immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic cells, GM-CSF is a survival factor for and activates the effectors functions of granulocytes, monocytes/macrophages and eosinophils.
Synonyms: Granulocyte/Macrophage-Colony Stimulating Factor, GMCSF

Poids moléculaire: 15-19 kDa, observed by non-reducing SDS-PAGE.

UniProt: Q14AD9

Pathways: Signalistation JAK/STAT, Cellular Response to Molecule of Bacterial Origin