CCL16 Protein (AA 24-120)

N° du produit ABIN2017934

Détail du produit

Antigène: CCL16 (Chemokine (C-C Motif) Ligand 16 (CCL16))

Type de proteíne: Recombinant

Activité biologique: Active

Attributs du protein: AA 24-120

Origine: Humain

Source: CHO Cells

Attributs du produit: The EC50 value of human HCC-4/CCL16 on Ca2+ mobilization assay in CHO-K1/Ga15/hCCR1 cells (human Ga15 and human CCR1 stably expressed in CHO-K1 cells) is less than 1.5 μg/mL.

Pureté: > 98 % as analyzed by SDS-PAGE.

niveau d'endotoxine: < 0.2 EU/μg, determined by LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstituted in ddH2O or PBS at 100 μg/mL.

Buffer: Lyophilized after extensive dialysis against PBS.

Stock: -80 °C

Stockage commentaire: Lyophilized recombinant human HCC4/CCL16 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human HCC4/CCL16 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

Date de péremption: 6 months

Détail du antigène

Antigène: CCL16 (Chemokine (C-C Motif) Ligand 16 (CCL16))

Autre désignation: HCC-4/CCL16 (CCL16 Produits)

Sujet: Human HCC4, also named NCC4and Chemokine (C-C motif) ligand 16 (CCL16) is a small cytokine belonging to the CC chemokine family that is known under several pseudonyms, including Liver-expressed chemokine (LEC) and Monotactin-1 (MTN-1). It can signal through the CCR8 and CCR1 receptors, and it is chemotactic towards monocytes and lymphocytes but not neutrophils. HCC-4 is expressed weakly by some lymphocytes, including NK cells, T cells, and some T cell clones. The expression of HCC-4 in monocytes is greatly up-regulated in the presence of IL-10. HCC-4 induces a calcium flux in thp-1 cells that are desensitized prior to the expression of RANTES.
Synonyms: HCC-4/CCL16, Human

Poids moléculaire: 12 kDa, observed by reducing SDS-PAGE.