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IFNGR2 Protein (AA 28-247)

IFNGR2 Origine: Humain Hôte: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
N° du produit ABIN2017972
  • Antigène Voir toutes IFNGR2 Protéines
    IFNGR2 (Interferon gamma Receptor 2 (Interferon gamma Transducer 1) (IFNGR2))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Attributs du protein
    AA 28-247
    Origine
    • 7
    • 1
    Humain
    Source
    • 4
    • 2
    • 2
    CHO Cells
    Attributs du produit
    ED50 < 0.1 μg/mL, measured in a cell cytotoxicity assay using HT-29 (HTB-38) cells in the presence of 1 ng/mL human IFN-gamma.
    Pureté
    > 95 % as analyzed by SDS-PAGE.
    niveau d'endotoxine
    < 0.2 EU/μg, determined by LAL method.
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    Discover our top product IFNGR2 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Stock
    -80 °C
    Stockage commentaire
    Lyophilized recombinant Human IFN-gamma Receptor II remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human IFN-gamma Receptor II should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    Date de péremption
    6 months
  • Antigène
    IFNGR2 (Interferon gamma Receptor 2 (Interferon gamma Transducer 1) (IFNGR2))
    Abstract
    IFNGR2 Produits
    Synonymes
    Ifgr2 Protein, Ifgt Protein, AF-1 Protein, IFGR2 Protein, IFNGT1 Protein, interferon gamma receptor 2 Protein, Ifngr2 Protein, IFNGR2 Protein, LOC487739 Protein
    Sujet
    IFN-gamma Receptor II, also known as IFNGR2 and IFNGT1, is a transmembrane protein belonging to the type II cytokine receptor family. IFNGR2 is a non-ligand-binding beta chain of the IFN-gamma receptor. It is an integral part of the IFN-gamma signaling transduction pathway and is likely to interact with GAF, JAK1 and JAK2. Defects in IFNGR2 are a cause of autosomal recessive Mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection.
    Synonyms: IFNGR2, IFNGT1
    Poids moléculaire
    38-40 kDa, observed by reducing SDS-PAGE.
    UniProt
    P38484
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