NEU1 Protein (AA 48-415) (His tag)

N° du produit ABIN2115431

Détail du produit

Antigène: NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))

Type de proteíne: Recombinant

Attributs du protein: AA 48-415

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette NEU1 protéine est marqué à la His tag.

Fonction: Recombinant Human Sialidase-1/NEU-1 (C-6His)

Séquence: ENDFGLVQPL VTMEQLLWVS GRQIGSVDTF RIPLITATPR GTLLAFAEAR KMSSSDEGAK FIALRRSMDQ GSTWSPTAFI VNDGDVPDGL NLGAVVSDVE TGVVFLFYSL CAHKAGCQVA STMLVWSKDD GVSWSTPRNL SLDIGTEVFA PGPGSGIQKQ REPRKGRLIV CGHGTLERDG VFCLLSDDHG ASWRYGSGVS GIPYGQPKQE NDFNPDECQP YELPDGSVVI NARNQNNYHC HCRIVLRSYD ACDTLRPRDV TFDPELVDPV VAAGAVVTSS GIVFFSNPAH PEFRVNLTLR WSFSNGTSWR KETVQLWPGP SGYSSLATLE GSMDGEEQAP QLYVLYEKGR NHYTESISVA KISVYGTLVD HHHHHH

Attributs du produit: Recombinant Human Sialidase-1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Glu48-Leu415) of Human NEU1 fused with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: -80 °C

Stockage commentaire: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))

Autre désignation: Sialidase-1 (NEU1 Produits)

Synonymes: NANH Protein, NEU Protein, SIAL1 Protein, MGC81958 Protein, AA407268 Protein, AA407316 Protein, Aglp Protein, Apl Protein, Bat-7 Protein, Bat7 Protein, G9 Protein, Map-2 Protein, Neu Protein, Neu-1 Protein, neuraminidase 1 Protein, neuraminidase 1 (lysosomal sialidase) L homeolog Protein, NEU1 Protein, neu1.L Protein, neu1 Protein, Neu1 Protein

Sujet: Sialidase-1 belongs to the N-acetyl-a neuraminidase family. Sialidase-1 is expressed in many tissues, it is highly expressed in the pancreas, and weakly expressed in the brain. Sialidase-1 is a lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. Deficiencies in the human enzyme Sialidase-1 leads to sialidosis, a rare lysosomal storage disease. Sialidase-1 has been shown to interact with Cathepsin A (protective protein), β-galactosidase and N-acetylgalactosamine-6-sulfate sulfatase in a multienzyme complex.
Synonyms: Sialidase-1, Acetylneuraminyl Hydrolase, G9 Sialidase, Lysosomal Sialidase, N-Acetyl-Alpha-Neuraminidase 1, NEU1, NANH

Poids moléculaire: 41.27 kDa

UniProt: Q99519

Pathways: SARS-CoV-2 Protein Interactome