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MTHFS Protein (AA 1-203) (His tag)

MTHFS Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN2115468
  • Antigène Voir toutes MTHFS Protéines
    MTHFS (5,10-Methenyltetrahydrofolate Synthetase (5-Formyltetrahydrofolate Cyclo-Ligase) (MTHFS))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-203
    Origine
    • 6
    • 1
    • 1
    Humain
    Source
    • 5
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette MTHFS protéine est marqué à la His tag.
    Fonction
    Recombinant Human 5-Formyltetrahydrofolate Cyclo-Ligase/MTHFS (C-6His)
    Séquence
    MAAAAVSSAK RSLRGELKQR LRAMSAEERL RQSRVLSQKV IAHSEYQKSK RISIFLSMQD EIETEEIIKD IFQRGKICFI PRYRFQSNHM DMVRIESPEE ISLLPKTSWN IPQPGEGDVR EEALSTGGLD LIFMPGLGFD KHGNRLGRGK GYYDAYLKRC LQHQEVKPYT LALAFKEQIC LQVPVNENDM KVDEVLYEDS STALEHHHHH H
    Attributs du produit
    Recombinant Human 5-formyltetrahydrofolate cyclo-ligase is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Ala203) of Human MTHFS fused with a 6His tag at the C-terminus..
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    Stérilité
    0.2 μm filtered
    niveau d'endotoxine
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product MTHFS Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM Tris,200 mM Nacl,1 mM DTT,50 % Glycerol, pH 8.0.
    Agent conservateur
    Dithiothreitol (DTT)
    Précaution d'utilisation
    This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Stock
    -80 °C
    Stockage commentaire
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    MTHFS (5,10-Methenyltetrahydrofolate Synthetase (5-Formyltetrahydrofolate Cyclo-Ligase) (MTHFS))
    Autre désignation
    5-Formyltetrahydrofolate Cyclo-Ligase (MTHFS Produits)
    Synonymes
    MTHFS Protein, 1110034I12Rik Protein, 2310020H23Rik Protein, AI119695 Protein, HsT19268 Protein, 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) Protein, methenyltetrahydrofolate synthetase Protein, 5-formyltetrahydrofolate cyclo-ligase (predicted) Protein, 5-formyltetrahydrofolate cyclo-ligase Protein, 5, 10-methenyltetrahydrofolate synthetase Protein, MTHFS Protein, SPBC1703.08c Protein, ZMO0215 Protein, LBA1507 Protein, Rxyl_1321 Protein, MEMAR_RS07640 Protein, Mjls_4669 Protein, STROP_RS03755 Protein, Mext_0779 Protein, AMF_RS07350 Protein, CKC_02040 Protein, Mthfs Protein
    Sujet
    5-formyltetrahydrofolate cyclo-ligase (MTHFS) belongs to the 5-formyltetrahydrofolate cyclo-ligase family. It is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, contributes to tetrahydrofolate metabolism. MTHFS helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion.
    Synonyms: 5-formyltetrahydrofolate cyclo-ligase,5,10-methenyl-tetrahydrofolate synthetase,MTHFS,Methenyl-THF synthetase
    Poids moléculaire
    24.3 kDa
    UniProt
    P49914
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