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BCL2L1 Protein (AA 2-212) (GST tag)

BCL2L1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant >92 % as determined by SDS-PAGE.
N° du produit ABIN2180640
  • Antigène Voir toutes BCL2L1 Protéines
    BCL2L1 (BCL2-Like 1 (BCL2L1))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 2-212
    Origine
    • 10
    • 4
    • 2
    Humain
    Source
    • 11
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette BCL2L1 protéine est marqué à la GST tag.
    Séquence
    AA 2-212
    Attributs du produit
    This protein carries a GST tag at the N-terminus. The protein has a calculated MW of 50.5 kDa. The protein migrates as 46 kDa under reducing (R) condition (SDS-PAGE).
    Pureté
    >92 % as determined by SDS-PAGE.
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product BCL2L1 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    20 mM Tris, 100 mM NaCl, pH 7.5 with 10 mM GSH
    Conseil sur la manipulation
    Please avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Antigène
    BCL2L1 (BCL2-Like 1 (BCL2L1))
    Autre désignation
    Bcl-X (BCL2L1 Produits)
    Synonymes
    BCL-XL/S Protein, BCL2L Protein, BCLX Protein, BCLXL Protein, BCLXS Protein, Bcl-X Protein, PPP1R52 Protein, bcl-xL Protein, bcl-xS Protein, Bcl(X)L Protein, Bcl-XL Protein, Bcl-Xs Protein, Bcl2l Protein, BclX Protein, bcl-x Protein, Bcl-xl Protein, Bclx Protein, bcl-X Protein, Bcl-xL Protein, BCL-XL Protein, BCL2L1 Protein, bcl-XL Protein, bcl-x(l) Protein, bcl-xl/s Protein, bcl-xs Protein, bcl2l Protein, bclx Protein, bclxl Protein, xR11 Protein, bcl-xl Protein, blp1 Protein, cb1021 Protein, zfBLP1 Protein, BCL2 like 1 Protein, BCL2-like 1 Protein, Bcl2-like 1 Protein, BCL2-like 1 L homeolog Protein, bcl2-like 1 Protein, BCL2L1 Protein, Bcl2l1 Protein, bcl2l1 Protein, bcl2l1.L Protein
    Sujet
    Bcl-2-like protein 1 (BCL2L1), is also known as Apoptosis regulator Bcl-X (Bcl-XL). BCL2L1 / Bcl-XL is a homodimer protein and belongs to the Bcl-2 family. BCL2L1 is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. BCL2L1 is a potent inhibitor of cell death. BCL2L1 Inhibits activation of caspases. BCL2L1 appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. BCL2L1 / Bcl-XL also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.
    Poids moléculaire
    50.6 kDa
    Pathways
    Apoptose, Negative Regulation of intrinsic apoptotic Signaling
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