CD4 Protein (CD4) (AA 26-390) (Fc Tag)

N° du produit ABIN2180784

Détail du produit

Antigène: CD4

Type de proteíne: Recombinant

Activité biologique: Active

Attributs du protein: AA 26-390

Origine: Macaque rhésus

Source: HEK-293 Cells

Purification/Conjugué: Cette CD4 protéine est marqué à la Fc Tag.

Séquence: AA 26-390

Attributs du produit: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 67 kDa. The protein migrates as 70-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Pureté: >95 % as determined by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Tris with Glycine, Arginine and NaCl,  pH 7.5

Conseil sur la manipulation: Please avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).

Détail du antigène

Antigène: CD4

Autre désignation: CD4 (CD4 Produits)

Sujet: T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.

Poids moléculaire: 67.0 kDa

UniProt: G7N5T8

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events