DPP4 Protein (AA 34-766) (His tag)
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- Antigène Voir toutes DPP4 Protéines
- DPP4 (Dipeptidyl-Peptidase 4 (DPP4))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 34-766
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette DPP4 protéine est marqué à la His tag.
- Séquence
- AA 34-766
- Attributs du produit
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 85.4 kDa. The protein migrates as 95 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Pureté
- >95 % as determined by SDS-PAGE.
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product DPP4 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Conseil sur la manipulation
- Please avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- Lyophilized Protein should be stored at -20 °C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20 °C or -70 °C. Avoid repeated freeze-thaw cycles.
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- Antigène
- DPP4 (Dipeptidyl-Peptidase 4 (DPP4))
- Autre désignation
- DPPIV (DPP4 Produits)
- Synonymes
- ADABP Protein, ADCP2 Protein, CD26 Protein, DPPIV Protein, TP103 Protein, MGC81966 Protein, MOP9.8 Protein, MOP9_8 Protein, DPP4 Protein, si:ch73-2d23.3 Protein, Cd26 Protein, Dpp-4 Protein, THAM Protein, dipeptidyl peptidase 4 Protein, dipeptidyl-peptidase 4 S homeolog Protein, prolyl oligopeptidase family protein Protein, dipeptidyl-peptidase 4 Protein, dipeptidylpeptidase 4 Protein, DPP4 Protein, dpp4.S Protein, AT5G24260 Protein, dpp4 Protein, Dpp4 Protein
- Sujet
- Dipeptidyl peptidase-IV (DPPIV) is also known as adenosine deaminase complexing protein 2, DPPIV or CD26 is antigenic enzyme expressed on the surface of most cell types and is associated with immune regulation, signal transduction and apoptosis. It is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. The substrates of DPPIV are proline (or alanine)-containing peptides and include growth factors, chemokines, neuropeptides, and vasoactive peptides. DPPIV plays a major role in glucose metabolism. It is responsible for the degradation of incretins such as GLP-1. DPPIV plays an important role in tumor biology, and is useful as a marker for various cancers, with its levels either on the cell surface or in the serum increased in some neoplasms and decreased in others. DPPIV also binds the enzyme adenosine deaminase specifically and with high affinity. The significance of this interaction has yet to be established.
- Poids moléculaire
- 85.7 kDa
- NCBI Accession
- NP_001926
- Pathways
- Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity
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