HSA Protein (AA 25-609) (His tag)

N° du produit ABIN2181228

Détail du produit

Antigène: HSA (Human Serum Albumin (HSA))

Type de proteíne: Recombinant

Attributs du protein: AA 25-609

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette HSA protéine est marqué à la His tag.

Séquence: AA 25-609

Attributs du produit: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 67.3 kDa. The protein migrates as 66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Pureté: >95 % as determined by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Conseil sur la manipulation: Please avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).

Référence

Siaw, Raghunath, Dyer: "Peripheral Protein Unfolding Drives Membrane Bending." dans: Langmuir : the ACS journal of surfaces and colloids, Vol. 34, Issue 28, pp. 8400-8407, (2019) (PubMed).

Happonen, Hauri, Svensson Birkedal, Karlsson, de Neergaard, Khakzad, Nordenfelt, Wikström, Wisniewska, Björck, Malmström, Malmström: "A quantitative Streptococcus pyogenes-human protein-protein interaction map reveals localization of opsonizing antibodies." dans: Nature communications, Vol. 10, Issue 1, pp. 2727, (2019) (PubMed).

Détail du antigène

Antigène: HSA (Human Serum Albumin (HSA))

Autre désignation: HSA (HSA Produits)

Synonymes: PRO0883 Protein, PRO0903 Protein, PRO1341 Protein, albumin Protein, ALB Protein

Sujet: Serum albumin (SA) is also known as ALB, which is the main protein of plasma and has a good binding capacity for water,Ca2+,Na+,K+,fatty acids,hormones, bilirubin and drugs.The main function of SA is the regulation of the colloidal osmotic pressure of blood. As Major zinc transporter in plasma, SA typically binds about 80 % of all plasma zinc. A variant structure of albumin could lead to increased binding of zinc resulting in an asymptomatic augmentation of zinc concentration in the blood. Defects in serum albumin can cause familial dysalbuminemic hyperthyroxinemia which is a form of euthyroid hyperthyroxinemia that is due to increased affinity of serum albumin for T4. It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.

Poids moléculaire: 67.4 kDa

NCBI Accession: NP_000468