PLAUR Protein (AA 23-303) (His tag)

N° du produit ABIN2181889

Détail du produit

Antigène: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Type de proteíne: Recombinant

Attributs du protein: AA 23-303

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette PLAUR protéine est marqué à la His tag.

Séquence: AA 23-303

Attributs du produit: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 32.1 kDa. The protein migrates as 44-48 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Pureté: >92 % as determined by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Conseil sur la manipulation: Please avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).

Détail du antigène

Antigène: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Autre désignation: uPAR (PLAUR Produits)

Synonymes: Cd87 Protein, u-PAR Protein, uPAR Protein, CD87 Protein, U-PAR Protein, UPAR Protein, URKR Protein, Par Protein, Plaur3 Protein, uPAR-2 Protein, uPAR-3 Protein, PLAUR Protein, plasminogen activator, urokinase receptor Protein, Plaur Protein, PLAUR Protein

Sujet: Urokinase plasminogen activator surface receptor (U-PAR) is also known as PLAUR, Monocyte activation antigen Mo3, CD antigen CD87. PLAUR contains three UPAR/Ly6 domains. U-PAR is expressed in neurons of the rolandic area of the brain (at protein level) and is also expressed in the brain. PLAUR / CD87 interacts with MRC2, SRPX2 and SORL1. PLAUR / UPAR acts as a receptor for urokinase plasminogen activator and plays a role in localizing and promoting plasmin formation. U-PAR mediates the proteolysis-independent signal transduction activation effects of U-PA.

Poids moléculaire: 32.3 kDa

Pathways: Inositol Metabolic Process