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VCAM1 Protein (AA 25-697) (His tag)

VCAM1 Origine: Humain Hôte: HEK-293 Cells Recombinant >92 % as determined by SDS-PAGE.
N° du produit ABIN2181894
  • Antigène Voir toutes VCAM1 Protéines
    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 25-697
    Origine
    • 27
    • 14
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain
    Source
    • 21
    • 19
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    HEK-293 Cells
    Purification/Conjugué
    Cette VCAM1 protéine est marqué à la His tag.
    Séquence
    AA 25-697
    Attributs du produit
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 75 kDa. The protein migrates as 80-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Pureté
    >92 % as determined by SDS-PAGE.
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product VCAM1 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Conseil sur la manipulation
    Please avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
  • Antigène
    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
    Autre désignation
    VCAM-1 (VCAM1 Produits)
    Synonymes
    CD106 Protein, INCAM-100 Protein, Vcam-1 Protein, VCAM1B Protein, fi76d06 Protein, wu:fi76d06 Protein, zgc:158875 Protein, VCAM1 Protein, vascular cell adhesion molecule 1 Protein, vascular cell adhesion molecule 1b Protein, VCAM1 Protein, Vcam1 Protein, vcam1b Protein, VCAM-1 Protein
    Sujet
    Vascular cell adhesion protein 1 (VCAM1) is also known as CD106, INCAM-100 and L1CAM, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. VCAM1 / CD106 contains 7 Ig-like C2-type (immunoglobulin-like) domains. CD106 / VCAM-1 is expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue. L1CAM / VCAM-1 is Important in cell-cell recognition and appears to function in leukocyte-endothelial cell adhesion. CD106 / VCAM1 interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1 / VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. INCAM-100 / VCAM1 binds to ECMV-D capsid proteins and acts as a receptor for this virus.
    Poids moléculaire
    74.9 kDa
    NCBI Accession
    NP_001069
    Pathways
    Carbohydrate Homeostasis
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