VEGFB Protein (AA 22-207) (His tag)
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- Antigène Voir toutes VEGFB Protéines
- VEGFB (Vascular Endothelial Growth Factor B (VEGFB))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 22-207
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette VEGFB protéine est marqué à la His tag.
- Séquence
- AA 22-207
- Attributs du produit
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 20.2 kDa. The protein migrates as 15-18 kDa and 33-35 kDa on a SDS-PAGE gel under reducing (R) condition.
- Pureté
- >90 % as determined by SDS-PAGE.
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product VEGFB Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Conseil sur la manipulation
- Please avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
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- Antigène
- VEGFB (Vascular Endothelial Growth Factor B (VEGFB))
- Autre désignation
- VEGF-B (VEGFB Produits)
- Synonymes
- VEGFL Protein, VRF Protein, VEGF-B Protein, Vrf Protein, vascular endothelial growth factor B Protein, VEGFB Protein, Vegfb Protein
- Sujet
- Vascular endothelial growth factor B (VEGFB) is also known as VEGF-related factor (VRF), is a secreted O-glycosylated protein, which belongs to the PDGF/VEGF growth factor family. VEGFB is expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas. VEGFB is growth factor for endothelial cells. VEGF-B seems to play a role only in the maintenance of newly formed blood vessels during pathological conditions. VEGF-B also plays an important role on several types of neurons. It is important for the protection of neurons in the retina and the cerebral cortex during stroke and of motoneurons during motor neuron diseases such as amyotrophic lateral sclerosis.VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.
- Poids moléculaire
- 20.3 kDa
- NCBI Accession
- NP_003368
- Pathways
- Signalisation RTK, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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