MTCH2 Protein (AA 29-174) (His tag)

N° du produit ABIN2468870

Détail du produit

Antigène: MTCH2 (Mitochondrial Carrier 2 (MTCH2))

Type de proteíne: Recombinant

Attributs du protein: AA 29-174

Origine: Souris

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette MTCH2 protéine est marqué à la His tag.

Application: Western Blotting (WB), ELISA, Mass Spectrometry (MS), Neutralization (Neut)

Pureté: ~95 %

Information d'application

Indications d'application: This recombinant protein can be used for WB, ELISA, MS and neutralization assays.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 1X PBS containing 0.1 % SDS

Conseil sur la manipulation: Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Stock: -80 °C

Stockage commentaire: Store in working aliquots at -70 °C.

Détail du antigène

Antigène: MTCH2 (Mitochondrial Carrier 2 (MTCH2))

Autre désignation: MTCH2 (MTCH2 Produits)

Synonymes: MIMP Protein, SLC25A50 Protein, Hspc032 Protein, fi20c06 Protein, fj35g12 Protein, wu:fi20c06 Protein, wu:fj35g12 Protein, 2310034D24Rik Protein, 4930539J07Rik Protein, HSPC032 Protein, mitochondrial carrier 2 Protein, mitochondrial carrier 2 L homeolog Protein, mitochondrial carrier homolog 2 Protein, MTCH2 Protein, mtch2.L Protein, Mtch2 Protein, mtch2 Protein

Sujet: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer (reviewed in 1). The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death (reviewed in 2 and 3). MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals (4-6), suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway. The doublet observed in the SDS-PAGE is likely due to incomplete removal of the signal sequence.

Poids moléculaire: 19 kDa (Calculated)

ID gène: 56428

NCBI Accession: NP_055157

OMIM: 5815347

UniProt: Q791V5