NR1I3 Protein (His tag)

N° du produit ABIN2566333

Détail du produit

Antigène: NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette NR1I3 protéine est marqué à la His tag.

Application: Western Blotting (WB)

Attributs du produit:

Measured by the ability of the immobilized protein to support the adhesion of mouse neutrophils. When 50000 cells/well are added to CXADR coated plates (4 μg/mL and 100μL/well ), approximately 20 % - 50 % will adhere specifically after 60 minutes at 37˚,C.

Pureté: >95 % as determined by SDS-PAGE.

Information d'application

Indications d'application: This recombinant protein can be used for WB. For research use only.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -80 °C,-20 °C

Stockage commentaire: Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.

Détail du antigène

Antigène: NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))

Autre désignation: CAR (NR1I3 Produits)

Synonymes: AA209988 Protein, AI551208 Protein, CAR Protein, CAR-beta Protein, Care2 Protein, ESTM32 Protein, MB67 Protein, CAR1 Protein, CXR Protein, nuclear receptor subfamily 1 group I member 3 Protein, nuclear receptor subfamily 1, group I, member 3 Protein, NR1I3 Protein, Nr1i3 Protein

Sujet: Coxsackie virus and adenovirus receptor (CXADR) is also known as CAR, is a type I transmembrane glycoprotein for group B coxsackie viruses and subgroup C adenoviruses, and belongs to the CTX family of the Ig superfamily. CAR is strongly expressed in the developing central nervous system. It functions as a homophilic and also as a heterophilic cell adhesion molecule through its interactions with extracellular matrix glycoproteins such as: fibronectin, agrin, laminin-1 and tenascin-R. Human CXADR protein contains a signal sequence, a extracellular domain (ECD) with a V- type (D1) and a C2- type (D2) Ig-like domain, a transmembrane segment and a intracellular domain. D1 is thought to be responsible for homodimer formation in trans within tight junctions, and is necessary and sufficient for adenovirus binding. Variants of CXADR are attached to the cell membrane by a GPI- anchor.

Poids moléculaire: 24.9 kDa

ID gène: 1525

NCBI Accession: NP_001329

UniProt: P78310

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway