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PRMT2 Protein (DYKDDDDK Tag)

PRMT2 Origine: Humain Hôte: Baculovirus Recombinant EAA, ScA
N° du produit ABIN2669657
  • Antigène Voir toutes PRMT2 Protéines
    PRMT2 (Protein Arginine Methyltransferase 2 (PRMT2))
    Type de proteíne
    Recombinant
    Origine
    • 4
    • 1
    • 1
    • 1
    Humain
    Source
    • 2
    • 2
    • 2
    • 1
    Baculovirus
    Purification/Conjugué
    Cette PRMT2 protéine est marqué à la DYKDDDDK Tag.
    Application
    Enzyme Activity Assay (EAA), Screening Assay (ScA)
    Attributs du produit
    Recombinant PRMT2 (accession number NP_996845.1) was expressed in Sf9 cells and contains an N-terminal FLAG tag with an observed molecular weight of 47.6 kDa.
    Top Product
    Discover our top product PRMT2 Protéine
  • Indications d'application
    Recombinant PRMT2 is suitable for use in the study of enzyme kinetics, inhibitor screening, and selectivity profiling. Specific Activity: PRMT2 methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, and histone H4.May methylate H3R8 and H4.
    Restrictions
    For Research Use only
  • Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
    Stock
    -80 °C
    Stockage commentaire
    Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation.
  • Antigène
    PRMT2 (Protein Arginine Methyltransferase 2 (PRMT2))
    Autre désignation
    PRMT2 (PRMT2 Produits)
    Synonymes
    PRMT2 Protein, DKFZp459N1919 Protein, HRMT1L1 Protein, Hrmt1l1 Protein, AI504737 Protein, protein arginine methyltransferase 2 Protein, protein arginine methyltransferase 2 L homeolog Protein, protein arginine N-methyltransferase 2 Protein, PRMT2 Protein, Prmt2 Protein, prmt2.L Protein
    Sujet
    PRMT2 (Protein Arginine Methyltransferase 2) is a member of the protein arginine N-methyltransferase (PRMT) family that is capable of monomethylating and asymmetrically dimethylating arginine residues. PRMT2 methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, and histone H4. PRMT2, along with NCOA2, acts as a coactivator of androgen receptor (AR)-mediated transactivation. PRMT2 also acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation. PRMT2 enhances PGR, PPARY, RARA-mediated transactivation and may inhibit NFκB transcription and promote apoptosis. PRMT2 is known to repress E2F1 transcriptional activity in an Rb-dependent manner and may be involved in growth regulation.
    Poids moléculaire
    47.6 kDa
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding
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